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Table 2 Association of ASPN D repeat and CILP rs2073711 polymorphism with hand OA

From: Functional polymorphisms in asporin and CILP together with joint loading predispose to hand osteoarthritis

ASPN D15 & CILP rs2073711

N (casesa)

OR (95% CI)b

Stratified by occupation

Dentists / Teachers

OR (95% CI)

Stratified by variation in dental tasks (dentists only) - Low variation

OR (95% CI)

No D15 & CC + CT

300 (54)

1.0

1.0

1.0

At least one D15 or TT

224 (53)

1.43 (0.92–2-23)

2.48 (1.27–4.85), p = 0.008c/ 0.91 (0.50–1.67), p = 0.77

3.00 (1.35–6.66), p = 0.007d

  1. Logistic regression analysis; CI, confidence interval; OR, odds ratio
  2. aSymmetrical OA of grade 2 or more in at least two joints pairs
  3. bAdjusted for age (years) and occupation
  4. cBonferroni corrected p = 0.04
  5. dBonferroni corrected p = 0.035
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BMC Genomic Data

ISSN: 2730-6844

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