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Table 5 Top ten targeter TFs for Rhesus monkey (that are connected with maximum number of gene-modules and that regulate maximum number of genes from the connected gene-modules) with information of their maximum number of regulated genes as well as gene-modules, and verified information of them

From: Detecting TF-miRNA-gene network based modules for 5hmC and 5mC brain samples: a intra- and inter-species case-study between human and rhesus

SL. No.

TFs

Number of connected gene-modules

Number of regulated genes

Name of the connected gene-modules (number of regulated genes in the modules)

Disease and Disease-verified information of TFs

Status of TFs

1

BAZ2B

2

11

Blue (9), Turquoise (2).

 

Unknown

2

E2F4

2

10

Blue (2), Turquoise (8).

SIV encephalitis [45]

Known

3

ZBTB20

2

10

Blue (5), Turquoise (5).

Age associated brain disease [46]

Known

4

FOXM1

2

8

Blue (2), Turquoise (6).

Glioma [47]

Known

5

RCOR3

2

7

Blue (6), Turquoise (1).

-

Unknown

6

SSRP1

2

7

Blue (4), Turquoise (3).

Kaposi’s Sarcoma [48]

Known

7

TEDP1

2

6

Blue (3), Turquoise (3).

Accute or chronic neurodegenerative diseases [49]

Known

8

ATF1

2

6

Blue (5), Turquoise (1).

-

Unknown

9

ZNF207

2

5

Blue (2), Turquoise (3).

Epigenetic regulation of puberty [50]

Known

10

MYBL2

2

5

Blue (2), Turquoise (3).

Kaposi Sarcoma and effecting sexual growth [51]

Known