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Table 5 Top ten targeter TFs for Rhesus monkey (that are connected with maximum number of gene-modules and that regulate maximum number of genes from the connected gene-modules) with information of their maximum number of regulated genes as well as gene-modules, and verified information of them

From: Detecting TF-miRNA-gene network based modules for 5hmC and 5mC brain samples: a intra- and inter-species case-study between human and rhesus

SL. No. TFs Number of connected gene-modules Number of regulated genes Name of the connected gene-modules (number of regulated genes in the modules) Disease and Disease-verified information of TFs Status of TFs
1 BAZ2B 2 11 Blue (9), Turquoise (2).   Unknown
2 E2F4 2 10 Blue (2), Turquoise (8). SIV encephalitis [45] Known
3 ZBTB20 2 10 Blue (5), Turquoise (5). Age associated brain disease [46] Known
4 FOXM1 2 8 Blue (2), Turquoise (6). Glioma [47] Known
5 RCOR3 2 7 Blue (6), Turquoise (1). - Unknown
6 SSRP1 2 7 Blue (4), Turquoise (3). Kaposi’s Sarcoma [48] Known
7 TEDP1 2 6 Blue (3), Turquoise (3). Accute or chronic neurodegenerative diseases [49] Known
8 ATF1 2 6 Blue (5), Turquoise (1). - Unknown
9 ZNF207 2 5 Blue (2), Turquoise (3). Epigenetic regulation of puberty [50] Known
10 MYBL2 2 5 Blue (2), Turquoise (3). Kaposi Sarcoma and effecting sexual growth [51] Known