Table 1 Demographic characteristics of AA-DHS participants, by presence/absence of CAC
Variables | CAC 130 HU <10 (N = 346) | CAC 130 HU ≥10 (N = 345) | ALL (N = 691) | P-value | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
Mean | SD | Median | Mean | SD | Median | Mean | SD | Median | ||
Age (years) | 52.8 | 8.7 | 52.0 | 59.8 | 9.0 | 60.0 | 56.3 | 9.6 | 56.0 | <0.0001 |
Female (%) | 66.5 | 53.6 | 60.1 | 0.0006 | ||||||
African Ancestry proportion (%) | 76.4 | 14.9 | 78.9 | 73.8 | 16.0 | 76.4 | 75.1 | 15.5 | 78.0 | 0.05 |
Diabetes duration (years) | 8.4 | 6.1 | 7.0 | 12.2 | 9.3 | 10.0 | 10.3 | 8.1 | 8.0 | <0.0001 |
HbA1c (%) | 8.3 | 2.3 | 7.8 | 8.1 | 1.9 | 7.6 | 8.2 | 2.1 | 7.7 | 0.94 |
C-reactive protein (mg/dl) | 1.0 | 1.5 | 0.5 | 0.9 | 1.3 | 0.4 | 0.9 | 1.4 | 0.5 | 0.27 |
Glucose (mg/dl) | 154.7 | 68.8 | 138.0 | 148.9 | 67.1 | 132.0 | 151.7 | 68.0 | 136.0 | 0.19 |
Low density lipoprotein cholesterol (mg/dl) | 108.5 | 37.4 | 106.0 | 107.1 | 36.6 | 103.0 | 107.8 | 36.9 | 105.0 | 0.46 |
High density lipoprotein cholesterol (mg/dl) | 48.2 | 14.4 | 46.0 | 47.8 | 14.4 | 45.0 | 48.0 | 14.4 | 46.0 | 0.51 |
Triglycerides (mg/dl) | 128.2 | 112.0 | 104.0 | 128.2 | 130.4 | 100.0 | 128.2 | 121.5 | 102.0 | 0.66 |
Body Mass Index (kg/m2) | 35.9 | 8.6 | 34.6 | 34.4 | 8.2 | 32.9 | 35.1 | 8.4 | 33.7 | 0.02 |
CAC 90 (Hounsfield unit) | 8.8 | 16.1 | 1.5 | 1212.0 | 1810.9 | 442.0 | 609.4 | 1413.3 | 44.0 | NA |
CAC 130 (Hounsfield unit) | 0.8 | 1.8 | 0.0 | 445.1 | 646.1 | 190.5 | 222.6 | 507.5 | 9.5 | NA |
ACE inhibitor use (%) | 46.8 | 51.3 | 49.1 | 0.25 | ||||||
Current smoker (%) | 20.3 | 25.2 | 22.8 | 0.007 | ||||||
Past smoker (%) | 31.7 | 40.2 | 36.0 | 0.001 | ||||||
Hypertension (%) | 78.0 | 89.1 | 83.6 | 0.0001 | ||||||
Lipid-lowering medication (%) | 39.5 | 53.4 | 46.4 | 0.0004 | ||||||