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Table 3 Simulation results for the test statistic T under the alternative hypothesis

From: On the impact of relatedness on SNP association analysis

Study

\(\bar {T}\)

\(\bar {S}^{2}\)

μ

HapMap

1.619 (0.037)

1.343 (0.095)

1.600

SFS1

1.619 (0.036)

1.336 (0.112)

1.600

SFS2

4.472 (0.036)

1.330 (0.076)

4.468

Sorbs

4.420 (0.039)

1.432 (0.148)

4.418

SFS3

4.479 (0.046)

2.030 (0.162)

4.468

  1. The test statistics \(\bar {T}\) averaged over replicates and SNPs and the average of the empirical variances \(\bar {S}^{2}\) are compared between HapMap, SFS1 (synthetic family study 1), SFS2, Sorbs and SFS3 assuming the alternative hypothesis with \(R^{2}_{\mathrm {s}}=0.02\) and heritability \(R^{2}_{\mathrm {h}}=0.9\). Standard deviations are presented in parentheses. We further provide the expected value μ of the test statistic T