From: Evaluating genetic ancestry and self-reported ethnicity in the context of carrier screening
Sickle Cell Anemia | ||||
 | carrier rate < threshold | carrier rate > threshold | p-value | African Ancestry Threshold (80th percentile) |
African | 6.760% | 15.741% | 0.00605 | 93.439% |
Latin American | 1.261% | 4.587% | 0.00372 | 18.677% |
Cystic Fibrosis | ||||
 | carrier rate < threshold | carrier rate > threshold | p-value | European Ancestry Threshold (80th percentile) |
African | 1.631% | 6.482% | 0.01095 | 19.928% |
Latin American | 1.606% | 3.670% | 0.06128 | 68.715% |
GJB2-Related Nonsyndromic Hearing Loss | ||||
 | carrier rate < threshold | carrier rate > threshold | p-value | European Ancestry Threshold (80th percentile) |
African | 1.399% | 5.556% | 0.01870 | 19.928% |
Latin American | 3.440% | 3.670% | 0.83750 | 68.715% |