TY - JOUR AU - Nowacka-Woszuk, Joanna AU - Madeja, Zofia E. AU - Chmurzynska, Agata PY - 2017 DA - 2017/08/15 TI - Prenatal caloric restriction alters lipid metabolism but not hepatic Fasn gene expression and methylation profiles in rats JO - BMC Genetics SP - 78 VL - 18 IS - 1 AB - Undernutrition is an increasingly common problem. Insufficient calorie intake and nutrient deficiencies during pregnancy may have an impact not only on the mother, but may also alter metabolism in the infant. In this study, we have applied a calorie-restricted diet during gestation and examined its effect on hepatic Fasn mRNA and DNA methylation profiles in rats and their female progeny. The body composition and blood lipid profiles were also evaluated in both generations. SN - 1471-2156 UR - https://doi.org/10.1186/s12863-017-0544-0 DO - 10.1186/s12863-017-0544-0 ID - Nowacka-Woszuk2017 ER -