Polymorphism/ allele | Suicide risk categories |
---|
No Bonferroni correction (α = 0.05) | With Bonferroni correction (α =0.0056) |
---|
Genotype | Allelic | Genotype | Allelic |
---|
STin2.VNTRs
| Â | *0.0285 | Â | 0.0285 |
5-HTTLPR
| Â | *0.0174 | Â | 0.0174 |
rs25531
| Â | 0.6125 | Â | 0.6125 |
5-HTTLPR-rs25531
| 0.0732 | Â | 0.0732 | Â |
L
A
| Â | *0.0068 | Â | 0.0068 |
S
A
| Â | *0.0046 | Â | *0.0046 |
L
G
| Â | 0.3491 | Â | 0.3491 |
S
G
| Â | 0.5686 | Â | 0.5686 |
Func_Comb | *0.0145 | Â | 0.0145 | Â |
-
p values were corrected for study site, socio-economic status and major depressive disorder
- *Significant effect, Func_Comb = Functional combination (over expressing (L
A
, S
A
) vs lower expressing (L
G
, S
G
alleles). The STin2.VNTRs, serotonin transporter intron 2 variable number of tandem repeats, rs25531, A to G single nucleotide polymorphism at position 25,531 of the serotonin transporter gene, 5-HTTLPR-rs25531, Serotonin transporter linked polymorphic region –rs25531 haplotype