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Table 4 Association between the 5-HTTLPR, rs25531 and STin2. VNTR and increased suicidal risk

From: Association between serotonin transporter gene polymorphisms and increased suicidal risk among HIV positive patients in Uganda

Polymorphism/ allele Suicide risk categories
No Bonferroni correction (α = 0.05) With Bonferroni correction (α =0.0056)
Genotype Allelic Genotype Allelic
STin2.VNTRs   *0.0285   0.0285
5-HTTLPR   *0.0174   0.0174
rs25531   0.6125   0.6125
5-HTTLPR-rs25531 0.0732   0.0732  
L A   *0.0068   0.0068
S A   *0.0046   *0.0046
L G   0.3491   0.3491
S G   0.5686   0.5686
Func_Comb *0.0145   0.0145  
  1. p values were corrected for study site, socio-economic status and major depressive disorder
  2. *Significant effect, Func_Comb = Functional combination (over expressing (L A , S A ) vs lower expressing (L G , S G alleles). The STin2.VNTRs, serotonin transporter intron 2 variable number of tandem repeats, rs25531, A to G single nucleotide polymorphism at position 25,531 of the serotonin transporter gene, 5-HTTLPR-rs25531, Serotonin transporter linked polymorphic region –rs25531 haplotype