Fig. 2

Differentially expressed genes (DGEs) of Asiatic toads at high altitudes. a. Heatmaps of gene expression profiles for the four treatment groups. There are more plastic DEGs than fixed ones in any tissue, and the heart has more DEGs than other tissues, both fixed and plastic. b. Venn-diagram of fixed and plastic DEGs among three tissues. Most DEGs are tissue-specific. c. Spearman rank correlations between O_LOW and O_HIGH treatment groups (fixed DEGs) and between F_LOW and F_HIGH treatment groups (plastic DEGs). Correlation coefficients are smaller among plastic DEGs than among fixed DEGs. The heart had the weakest correlation in both comparisons