Fig. 4
From: A strategy to apply quantitative epistasis analysis on developmental traits
brc-1 interactions. a Genes interacting with brc-1 and brd-1 in sex ratio. Red circles indicate genes associated with DNA repair in Gene Ontology; Blue lines indicate negative interactions (S < −0.8); Yellow lines indicate positive interactions (S > 0.8). b brc-1 genetic interactions in embryonic survival with (+) and without (−) MMS exposure. Heat map displays S scores. Blue, S < 0; Black, S = 0; Yellow, S > 0. c brc-1 genetic interactions in apoptotic germ cell numbers with or without MMS exposure. Left panels display the number of apoptotic cells of various RNAi on wild-type background. Right panels display the increase of apoptotic cells in brc-1 mutant background. Bars and error bars indicate mean and standard deviation. *, p < 0.05 in comparison with the control RNAi group. d Images of apoptotic germ cells showing that brc-1 mutation interacts synergistically with RNAi of C34F6.1. WT, wild-type. Scale bar, 10 μm