Table 3 Top 30 functional classifications of DEGs determined by comparisons with the GO and KEGG databases

 Carbohydrate metabolic process

GO:0005975

27

21

6

1.02E-11

 Hydrolase activity, hydrolyzing O-glycosyl czompounds

GO:0004553

22

16

6

2.08E-11

 Oxidation-reduction process

GO:0055114

45

29

16

5.83E-11

 Metabolic process

GO:0008152

38

28

10

6.64E-09

 Oxidoreductase activity

GO:0016491

34

24

10

9.51E-09

 Pyrimidine nucleoside metabolic process

GO:0006213

5

0

5

4.29E-07

 Pyrimidine nucleobase metabolic process

GO:0006206

5

0

5

4.29E-07

 transferase activity, transferring pentosyl groups

GO:0016763

5

0

5

4.29E-07

 Phosphorylase activity

GO:0004645

5

0

5

4.29E-07

 Pyrimidine-nucleoside phosphorylase activity

GO:0016154

5

0

5

4.29E-07

 Respiratory chain

GO:0070469

6

3

3

4.52E-07

 ATP binding

GO:0005524

2

1

1

5.54E-07

 Electron transport chain

GO:0022900

6

3

3

1.11E-06

 NADH dehydrogenase (ubiquinone) activity

GO:0008137

5

2

3

2.59E-06

 ATP synthesis coupled electron transport

GO:0042773

4

2

2

4.24E-06

 Pentose-phosphate shunt

GO:0006098

4

4

0

8.27E-06

 Mitochondrion

GO:0005739

10

5

5

1.78E-05

 Enzyme regulator activity

GO:0030234

4

4

0

3.93E-05

 RNA binding

GO:0003723

3

0

3

4.27E-05

 Serine-type endopeptidase inhibitor activity

GO:0004867

8

5

3

4.69E-05

 Nucleic acid binding

GO:0003676

4

2

2

5.15E-05

 Regulation of catalytic activity

GO:0050790

4

4

0

5.98E-05

 Peptidoglycan catabolic process

GO:0009253

3

0

3

8.32E-05

 Hydrolase activity, acting on glycosyl bonds

GO:0016798

10

8

2

0.00010235

 Glutathione transferase activity

GO:0004364

4

4

0

0.00012431

 Respiratory electron transport chain

GO:0022904

3

2

1

0.00014634

 Catalytic activity

GO:0003824

31

24

7

0.00021324

 Intracellular

GO:0005622

4

3

1

0.00023455

 Carbohydrate binding

GO:0030246

14

9

5

0.00038725

 Metabolic pathways

ko01100

104

64

40

1.02E-31

 Chemical carcinogenesis

ko05204

18

12

6

1.21E-24

 Metabolism of xenobiotics by cytochrome P450

ko00980

16

11

5

1.57E-22

 Drug metabolism - cytochrome P450

ko00982

14

10

4

8.19E-20

 Starch and sucrose metabolism

ko00500

17

16

1

2.43E-18

 Steroid hormone biosynthesis

ko00140

12

6

6

1.62E-14

 Biosynthesis of secondary metabolites

ko01110

32

21

11

3.94E-14

 Glutathione metabolism

ko00480

11

10

1

5.47E-12

 Retinol metabolism

ko00830

11

4

7

2.68E-11

 Arachidonic acid metabolism

ko00590

10

6

4

1.06E-10

 Lysosome

ko04142

16

11

5

1.19E-10

 Phenylpropanoid biosynthesis

ko00940

6

5

1

1.20E-10

 Pentose phosphate pathway

ko00030

9

9

0

4.07E-10

 Ascorbate and aldarate metabolism

ko00053

7

7

0

4.19E-10

 Proteoglycans in cancer

ko05205

16

9

7

1.18E-09

 Degradation of aromatic compounds

ko01220

5

5

0

1.27E-09

 Microbial metabolism in diverse environments

ko01120

19

13

6

2.79E-09

 Cyanoamino acid metabolism

ko00460

5

4

1

6.96E-09

 Galactose metabolism

ko00052

8

8

0

2.02E-08

 Caprolactam degradation

ko00930

5

5

0

7.53E-08

 Carbon metabolism

ko01200

14

10

4

7.69E-08

 Glycine, serine and threonine metabolism

ko00260

9

6

3

1.12E-07

 Carbohydrate digestion and absorption

ko04973

6

6

0

2.12E-07

 Glycosaminoglycan degradation

ko00531

6

5

1

2.12E-07

 Linoleic acid metabolism

ko00591

5

2

3

4.02E-07

 Oxidative phosphorylation

ko00190

13

6

7

4.07E-07

 Cardiac muscle contraction

ko04260

7

4

3

4.62E-07

 Phenylalanine metabolism

ko00360

5

2

3

2.51E-06

 Drug metabolism - other enzymes

ko00983

6

3

3

3.10E-06