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Table 3 Top 30 functional classifications of DEGs determined by comparisons with the GO and KEGG databases

From: Comparative profiling of hepatopancreas transcriptomes in satiated and starving Pomacea canaliculata

GO term/pathway ID Counts of DEGs Up-regulated Down-regulated p-value
Based on the GO database
 Carbohydrate metabolic process GO:0005975 27 21 6 1.02E-11
 Hydrolase activity, hydrolyzing O-glycosyl czompounds GO:0004553 22 16 6 2.08E-11
 Oxidation-reduction process GO:0055114 45 29 16 5.83E-11
 Metabolic process GO:0008152 38 28 10 6.64E-09
 Oxidoreductase activity GO:0016491 34 24 10 9.51E-09
 Pyrimidine nucleoside metabolic process GO:0006213 5 0 5 4.29E-07
 Pyrimidine nucleobase metabolic process GO:0006206 5 0 5 4.29E-07
 transferase activity, transferring pentosyl groups GO:0016763 5 0 5 4.29E-07
 Phosphorylase activity GO:0004645 5 0 5 4.29E-07
 Pyrimidine-nucleoside phosphorylase activity GO:0016154 5 0 5 4.29E-07
 Respiratory chain GO:0070469 6 3 3 4.52E-07
 ATP binding GO:0005524 2 1 1 5.54E-07
 Electron transport chain GO:0022900 6 3 3 1.11E-06
 NADH dehydrogenase (ubiquinone) activity GO:0008137 5 2 3 2.59E-06
 ATP synthesis coupled electron transport GO:0042773 4 2 2 4.24E-06
 Pentose-phosphate shunt GO:0006098 4 4 0 8.27E-06
 Mitochondrion GO:0005739 10 5 5 1.78E-05
 Enzyme regulator activity GO:0030234 4 4 0 3.93E-05
 RNA binding GO:0003723 3 0 3 4.27E-05
 Serine-type endopeptidase inhibitor activity GO:0004867 8 5 3 4.69E-05
 Nucleic acid binding GO:0003676 4 2 2 5.15E-05
 Regulation of catalytic activity GO:0050790 4 4 0 5.98E-05
 Peptidoglycan catabolic process GO:0009253 3 0 3 8.32E-05
 Hydrolase activity, acting on glycosyl bonds GO:0016798 10 8 2 0.00010235
 Glutathione transferase activity GO:0004364 4 4 0 0.00012431
 Respiratory electron transport chain GO:0022904 3 2 1 0.00014634
 Catalytic activity GO:0003824 31 24 7 0.00021324
 Intracellular GO:0005622 4 3 1 0.00023455
 Carbohydrate binding GO:0030246 14 9 5 0.00038725
Based on the KEGG database
 Metabolic pathways ko01100 104 64 40 1.02E-31
 Chemical carcinogenesis ko05204 18 12 6 1.21E-24
 Metabolism of xenobiotics by cytochrome P450 ko00980 16 11 5 1.57E-22
 Drug metabolism - cytochrome P450 ko00982 14 10 4 8.19E-20
 Starch and sucrose metabolism ko00500 17 16 1 2.43E-18
 Steroid hormone biosynthesis ko00140 12 6 6 1.62E-14
 Biosynthesis of secondary metabolites ko01110 32 21 11 3.94E-14
 Glutathione metabolism ko00480 11 10 1 5.47E-12
 Retinol metabolism ko00830 11 4 7 2.68E-11
 Arachidonic acid metabolism ko00590 10 6 4 1.06E-10
 Lysosome ko04142 16 11 5 1.19E-10
 Phenylpropanoid biosynthesis ko00940 6 5 1 1.20E-10
 Pentose phosphate pathway ko00030 9 9 0 4.07E-10
 Ascorbate and aldarate metabolism ko00053 7 7 0 4.19E-10
 Proteoglycans in cancer ko05205 16 9 7 1.18E-09
 Degradation of aromatic compounds ko01220 5 5 0 1.27E-09
 Microbial metabolism in diverse environments ko01120 19 13 6 2.79E-09
 Cyanoamino acid metabolism ko00460 5 4 1 6.96E-09
 Galactose metabolism ko00052 8 8 0 2.02E-08
 Caprolactam degradation ko00930 5 5 0 7.53E-08
 Carbon metabolism ko01200 14 10 4 7.69E-08
 Glycine, serine and threonine metabolism ko00260 9 6 3 1.12E-07
 Carbohydrate digestion and absorption ko04973 6 6 0 2.12E-07
 Glycosaminoglycan degradation ko00531 6 5 1 2.12E-07
 Linoleic acid metabolism ko00591 5 2 3 4.02E-07
 Oxidative phosphorylation ko00190 13 6 7 4.07E-07
 Cardiac muscle contraction ko04260 7 4 3 4.62E-07
 Phenylalanine metabolism ko00360 5 2 3 2.51E-06
 Drug metabolism - other enzymes ko00983 6 3 3 3.10E-06