Table 1 Clinical characteristics of participants

Mean age (mean ± SEM)

26.6 ± 0.668

26.2 ± 0.673

24.8 ± 0.723

28.7 ± 1.108

24.6 ± 0.904

28.0 ± 0.947

0.708^a

0.002 ^{b, d, f}

0.6081^c

Age range (years)

16–42

16–46

16–40

16–42

16–42

17–46

 0

44 (45)

22 (23)

26 (49)

18 (41)

17 (34)

5 (11)

0.006^b

 1–5

53 (55)

70 (74)

27 (50)

26 (59)

31 (62)

39 (87)

0.400^c

  > 5

1 (1.1)

3 (3.2)

0 (0.0)

1 (2.2)

2 (4.0)

1 (2.2)

Mean CD4 (x10⁶/l) (n)

447 ± 28.2 (44)

427 ± 31.1 (47)

670 ± 154 (2)

437 ± 28.0 (42)

399 ± 66.9 (7)

432 ± 34.9 (40)

0.6346^a

0.431^b

0.9212^c

BMI (n)

31.5 ± 0.847 (73)

30.0 ± 0.889 (71)

30.4 ± 1.30 (35)

32.5 ± 1.10 (38)

29.8 ± 1.22 (35)

30.2 ± 1.30 (36)

0.2126^a

0.2148^b

0.179^c

MOD n (%)

<0.001^b

 ELCS

18 (19)

52 (55)

9 (17)

9 (20)

25 (50)

27 (60)

<0.001^c

 EMCS

55 (56)

24 (25)

32 (60)

23 (52)

13 (26)

11 (24)

 NVD

24 (25)

15 (16)

12 (23)

12 (27)

9 (18)

6 (13)

 TOTAL

97 (100)

91 (96)

53 (100)

44 (100)

47 (94)

44 (98)

- Systolic

158 ± 1.75 (86)

119 ± 1.32 (62)

157 ± 17.2 (50)

159 ± 2.17 N = 43

119 ± 8.81 (29)

119 ± 2.03 (33)

<.0.0001^a

<.0.0001^{b, e, f, g, h}

<.0.0001^c

- Diastolic

103 ± 1.24 (93)

74.7 ± 1.11 (62)

102 ± 13.5 (50)

104 ± 1.51 (43)

73.9 ± 8.76 (29)

75.3 ± 1.53 (33)

<.0.0001^a

<.0.0001^{b, e, f, g, h}

<.0.0001^c

Severe PE (%)

18 (34)

21 (48)

0.121^b

EOPE (%)

14 (26)

18 (40)

0.143^b

IL-2 (n)

265 ± 3.57 (17)

270 ± 0.949 (59)

273 ± 4.76 (7)

260 ± 4.59 (10)

274 ± 1.24 (29)

267 ± 1.21 (30)

0.1827^a

0.006^{b, d, f}

0.164 ^c

IL-4 (n)

251 ± 5.40 (18)

244 ± 1.90 (59)

258 ± 26.7 (8)

245 ± 5.97 (10)

248 ± 16.4 (29)

241 ± 2.14 (30)

0.2537^a

0.0579^b

0.4760^c

IL-6 (n)

150 ± 8.28 (18)

152 ± 4.29 (59)

174 ± 36.5 (7)

136 ± 7.90 (11)

154 ± 28.1 (29)

150 ± 6.83 (30)

0.8938^a

0.0057^b

0.1920^c

IL-10 (n)

138 ± 46.0 (16)

81.7 ± 10.2 (54)

237 ± 251 (7)

61.4 ± 10.5 (9)

95.9 ± 68.0 (29)

66.4 ± 15.8 (26)

0.249^a

0.085^b

IL-17a (n)

1520 ± 311 (16)

800 ± 31.5 (58)

785 ± 118 (8)

2250 ± 509 (8)

773 ± 36.2 (29)

827 ± 62.9 (29)

0.036^a

<0.0001^{b, f, h, i}

0.027^c

TNF-α (n)

186 ± 12.4 (19)

175 ± 4.01 (60)

203 ± 72.7 (8)

173 ± 10.3 (11)

186 ± 15.6 (29)

164 ± 6.78 (31)

0.416^a

0.0008^{b, d, g}

0.479^c

IFN-γ (n)

214 ± 11.1 (18)

281 ± 64.7 (60)

221 ± 70.5 (8)

209 ± 4.82 (10)

221 ± 15.4 (29)

336 ± 125 (31)

0.317^a

0.036^b

0.319^c