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Fig. 4 | BMC Genetics

Fig. 4

From: A compendium of human genes regulating feeding behavior and body weight, its functional characterization and identification of GWAS genes involved in brain-specific PPI network

Fig. 4

The fractions of genes classified according to tissue expression patterns and calculated for all protein-coding genes (Genome) or for all genes from the compendium (578_all_Compendium) and gene sets Publications, OMIM_allelic_variants, OMIM_all_text, GWAS meta-analysis, Syndromes. Panel a presents the fractions of genes classified into all six expression categories described in [42] and the category Not found. Panel b presents the fractions of genes belonging to three consolidated groups: (1) Expressed in all + Mixed; (2) Not detected + Not found; (3) Tissue elevated. The significances of the Chi-square test comparing the fractions of genes in test groups with the fractions in the whole-genome dataset are indicated with one (p-value < 0.05), two (p-value < 0.01), or three (p-value < 0.001) asterisks. The red and blue dotted lines in panel a and the orange dotted line in panel b denote the levels observed in the whole genome set of protein-coding genes

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ISSN: 2730-6844

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