Fig. 4
From: Regulatory single nucleotide polymorphisms (rSNPs) at the promoters 1A and 1B of the human APC gene
Analysis of activity of reporter constructs. The luciferase activity was measured by the dual-luciferase reporter assay kit (Promega, USA). Firefly luciferase activity was normalized to Renilla luciferase activity. The bars indicated the mean ± SE of the luciferase activity (N = 3–7). a Cell line HCT-116. Significant differences * p < 0,05 was assessed by Students t test, compared to promoter 1B (Student t-test). b Cell line K562. Significant differences *** p < 0,001 was assessed by Students t test, compared to promoter 1B. Significant differences # p < 0,05 was assessed by Students t test, compared to promoter 1A