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Table 1 Body weight, food intake, and tissue weight in A/J, A/J-12SM consomic mice and R2 and R3 congenic mice fed the high-fat diet

From: Genetic dissection of the fatty liver QTL Fl1sa by using congenic mice and identification of candidate genes in the liver and epididymal fat

  A/J A/J-12SM R2 R3
Body weight (g)
 0 weeks of feeding with the HFD (Initial) 21.9 ± 0.3 22.1 ± 0.3 21.4 ± 0.4 21.2 ± 0.5
 7 weeks of feeding with the HFD (Final) 39.4 ± 0.4 35.8 ± 0.7** 38.2 ± 0.9 35.6 ± 0.7**
Food intake (g/g BW/day)a
 3 weeks of feeding with the HFD 0.065 ± 0.003 0.065 ± 0.001 0.065 ± 0.002 0.071 ± 0.003
 6 weeks of feeding with the HFD 0.053 ± 0.002 0.058 ± 0.001 0.052 ± 0.001 0.056 ± 0.002
Weight of tissues (g/100 g BW)
 Liver 3.66 ± 0.07 2.99 ± 0.08** 3.40 ± 0.07 3.47 ± 0.10
 Subcutaneous fatb 3.86 ± 0.12 3.48 ± 0.12 3.73 ± 0.19 3.55 ± 0.17
 Epididymal fat 4.82 ± 0.18 6.24 ± 0.21** 5.35 ± 0.16 4.97 ± 0.18
 Mesenteric fat 3.60 ± 0.13 2.90 ± 0.11** 3.56 ± 0.17 3.32 ± 0.11
 Retroperitoneal fat 1.26 ± 0.06 1.52 ± 0.04** 1.20 ± 0.04 1.40 ± 0.07
  1. Each value is expressed as the mean ± SEM
  2. n = 13–16, ** p < 0.01, significant difference versus A/J strain by Dunnett’s test
  3. aBW, body weight
  4. bSubcutaneous fat was dissected between the root of the forefoot and the hind leg on right side of the body