BMC Genomic Data

Table 1 Mutations in CAN1 are mostly large-scale changes, while mutations in URA3 are mostly small-scale changes

From: Growth conditions that increase or decrease lifespan in Saccharomyces cerevisiae lead to corresponding decreases or increases in rates of interstitial deletions and non-reciprocal translocations

Sample	CAN1 mutations				URA3 mutations
	Untreated		+ MMS^a		Untreated		+ MMS^a
	N	Freq His⁺	N	Freq His⁺	N	Freq point Mutations^b	N	Freq point mutations^b
YPD	217	0.24	110	0.46	99	0.95	43	0.98
SC + 2 % Glucose	137	0.24	80	0.41	57	1.0	13	0.92
30 °C	102	0.28	66	0.47	27	0.96	16	1.0
10 % Glucose	111	0.21	83	0.46	33	0.97	50	0.94
0.3 M NaCl	135	0.26	81	0.41	46	1.0	39	0.97
3 % Acetate	98	0.18	78	0.33	37	0.81*	19	1.0
0.2 % Glucose	106	0.27	82	0.38	38	0.87	50	0.96
2 % Ethanol	108	0.39**	96	0.34	46	0.80*	40	0.95
YPD rad52∆	59	0.88***	NT^c	NT^c	25	0.96	NT^c	NT^c

^aChronic exposure to 200 μM (0.0022 %) MMS
^bScored as point mutation if yielded expected size URA3 PCR product
^cNot tested
Asterisks indicate levels of significance: * = p < 0.05, ** = p < 0.01, *** = p < 0.001

Back to article page

ISSN: 2730-6844

Contact us

General enquiries: journalsubmissions@springernature.com