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Table 1 Maternal and perinatal background characteristics of the study groups

From: An RGS2 3′UTR polymorphism is associated with preeclampsia in overweight women

  Preeclampsia Control  
Primipara Multipara Primipara Multipara Primipara Multipara
(n = 987) (n = 352) (n = 377) (n = 320) P values P values
Maternal characteristics
Age, y 30 (26/33) 33 (30/38) 29 (25/32) 31 (28/35) 0.020 <0.001
Body mass index, kg/m2 23.6 (21.2/27.3) [985] 24.8 (22.1/29.4) [351] 23.0 (21.0/25.7) 22.8 (20.7/26.2) 0.006 <0.001
Highest systolic blood pressure, mmHg 165 (153/178) 166 (156/180) 126 (119/134) 124 (117/131) <0.001 <0.001
Highest diastolic blood pressure, mmHg 109 (104/116) 109 (103/116) 83 (78/88) 81 (77/86) <0.001 <0.001
Highest proteinuria, g/24 h 3.1 (1.4/6.2) [887] 2.9 (1.1/5.6) [305] 1.0 (0.8/1.6) [4] 0.6 [2] N/A N/A
Smoking before pregnancy 172 (18.3) [941] 48 (14.6) [328] 90 (24.8) [363] 44 (14.5) [304] 0.008 0.954
Smoking during pregnancy 58 (6.1) [948] 26 (7.8) [333] 28 (7.5) [371] 26 (8.4) [308] 0.345 0.769
Chronic hypertension 151 (15.3) 85 (24.1)
Gestational diabetes mellitus 116 (11.8) 69 (19.6) 29 (7.7) 24 (7.5) 0.030 <0.001
Pregestational diabetes mellitus 24 (2.4) 16 (4.5) 4 (1.1) 1 (0.3) 0.136 <0.001
Placental weight, g 495 (400/600) [951] 500 (390/615) [338] 590 (500/669) [363] 628 (554/720) [314] <0.001 <0.001
Placental insufficiency 94 (9.5) 50 (14.2)
Perinatal characteristics
Gestational age at birth, weeks 37.9 (35.4/39.3) [986] 37.4 (34.6/39.0) 40.6 (39.6/41.3) 40.3 (39.4/41.1) <0.001 <0.001
Birth weight, g 2775 (2185/3280) 2790 (1882/3384) 3520 (3245/3851) 3730 (3416/4022) <0.001 <0.001
Relative birth weight (SD) −1.1 (−1.9/−0.4) [986] −1.1 (−1.9/0.0) [350] −0.2 (−0.7/0.5) 0.3 (−0.3/0.9) <0.001 <0.001
  1. Values for continuous variables are median (25th/75th percentile) and for categorical variables frequencies (%). Number of subjects with data is shown in brackets if different from the total number