Genetic effects of FASN, PPARGC1A, ABCG2 and IGF1 revealing the association with milk fatty acids in a Chinese Holstein cattle population based on a post genome-wide association study

Table 7 Additive, dominant and allele substitution effects of the SNPs on milk fatty acids traits of PPARGC1A, ABCG2 and IGF1 in Chinese Holstein cattle

Gene	Locus	Genetic effect	C10:0	C12:0	C14:0	C14:1	C16:0	C16:1	C18:0	C18:1n9c	C18:2n6c	CLA	C14 INDEX	C16 INDEX	C18 INDEX	SFA	UFA	SFA/UFA
PPARGC1A	rs109579682	a	0.081*	0.120**	0.159*	−0.012	0.019	−0.052	0.008	−0.445**	−0.005**	0.006	−0.193	−0.153*	−0.356	0.436*	−0.496*	0.034
		d	0.107*	0.080	−0.049	−0.000	−0.435	0.025	−0.016	0.108	−0.001**	0.003	0.052	0.150	0.075	−0.270	0.134	−0.009
		α	0.036	0.086*	0.179**	−0.012	0.200	−0.062*	0.015	−0.490**	−0.005*	0.005	−0.215	−0.216**	−0.387	0.549**	−0.552**	0.037
ABCG2	rs137757790	a	0.039	0.047	0.185**	0.011	0.232	0.004	−0.136	−0.392**	−0.013	−0.003	−0.059	−0.025	−0.021	0.413**	−0.390**	0.028
		d	0.031	0.022	0.106	0.008	0.106	0.047	−0.173	−0.020	0.002	0.012	0.005	0.112	0.312	0.104	0.055	0.000
		α	0.041	0.049	0.195**	0.012	0.241	0.008	−0.151	−0.393**	−0.013	−0.002	−0.058	−0.015	0.007	0.422**	−0.385**	0.028
IGF-1	rs109763947	a	−0.063*	−0.040	−0.050	−0.004	−0.115	0.055	−0.088	0.201	0.045	0.005	0.003	0.168**	0.290	−0.369*	0.317*	−0.028
		d	−0.026	−0.083	−0.097	0.007	−0.220	−0.023	0.037	0.482**	0.064	−0.006	0.117	−0.023	0.334	−0.414	0.523*	−0.033
		α	−0.060*	−0.030	−0.038	−0.005	−0.088	0.057	−0.093	0.142	0.037	0.006	−0.012	0.171**	0.250	−0.319	0.253	−0.024

Note: a means additive effect; d means dominant effect; α means allele substitution effect. The asterisk (*) means the additive, dominant or allele substitution effect of the locus indicated differ at P < 0.05 and the asterisk (**) means the additive, dominant or allele substitution effect of the locus indicated differ at P < 0.01

ISSN: 2730-6844