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Table 6 Additive, dominant and allele substitution effects of the nine SNPs on milk fatty acids traits of FASN in Chinese Holstein cattle

From: Genetic effects of FASN, PPARGC1A, ABCG2 and IGF1 revealing the association with milk fatty acids in a Chinese Holstein cattle population based on a post genome-wide association study

Locus

Genetic effect

C10:0

C12:0

C14:0

C14:1

C16:0

C16:1

C18:0

C18:1n9c

C18:2n6c

CLA

C14 INDEX

C16 INDEX

C18 INDEX

SFA

UFA

SFA/ UFA

rs136947640

a

−0.052

−0.011

0.315

0.070

−0.039

−0.056

0.169

−0.409

0.147*

0.000

0.462

−0.143

−0.570

0.390

−0.301

0.036

d

−0.093

−0.082

0.186

0.063

−0.164

0.007

0.127

−0.409

0.244**

0.015

0.470

0.057

−0.465

0.029

−0.113

0.016

α

−0.125

−0.075

0.461

0.120

−0.167

−0.050

0.269

−0.729

0.339**

0.012

0.831

−0.099

−0.934

0.412

−0.390

0.049

rs41919999

a

0.072*

0.074

0.192**

−0.011

−0.008

0.013

−0.186

−0.193

0.007

0.008

−0.226

0.024

0.194

0.150

−0.160

0.008

d

0.090*

0.123*

0.080

0.022

−0.111

−0.021

0.012

−0.267

−0.021

−0.003

0.116

−0.041

−0.245

0.224

−0.308

0.022

α

0.079**

0.084*

0.198**

−0.009

−0.017

0.012

−0.185

−0.214

0.005

0.007

−0.217

0.020

0.175

0.167

−0.183

0.010

rs132865003

a

−0.029

−0.020

0.034

0.024

−0.206

−0.014

0.058

0.246

0.027

−0.012

0.195

−0.009

0.030

−0.230

0.238

−0.011

d

−0.026

−0.018

0.004

0.006

−0.256

0.035

−0.022

0.162

0.089*

0.005

0.046

0.139

0.157

−0.373

0.274

−0.019

α

−0.047

−0.032

0.037

0.028

−0.376

0.009

0.043

0.354

0.087

−0.009

0.225

0.083

0.135

−0.479

0.421

−0.024

rs134340637

a

0.029

0.020

−0.034

−0.024

0.206

0.014

−0.058

−0.246

−0.027

0.012

−0.195

0.009

−0.030

0.230

−0.238

0.011

d

−0.026

−0.018

0.004

0.006

−0.256

0.035

−0.022

0.162

0.089*

0.005

0.046

0.139

0.157

−0.373

0.274

−0.019

α

0.047

0.032

−0.037

−0.028

0.376

−0.009

−0.043

−0.354

−0.087

0.009

−0.225

−0.083

−0.135

0.479

−0.421

0.024

rs41919992

a

−0.001

0.042

−0.022

0.008

0.297

−0.006

−0.007

−0.482**

0.012

0.004

0.080

−0.049

−0.326

0.350

−0.475*

0.033

d

0.139**

0.250**

0.418**

0.030

0.510

−0.064

−0.235

−1.266**

0.010

−0.002

−0.022

−0.271**

−0.524

1.142**

−1.309**

0.091

α

0.058

0.148*

0.155

0.021

0.513

−0.033

−0.107

−1.018**

0.016

0.003

0.071

−0.163

−0.547

0.834*

−1.029**

0.071

rs133498277

a

−0.011

0.032

−0.048

0.006

0.324

1.796

0.041

−0.453*

−0.003

0.003

0.081

−0.068

−0.384

0.376

−0.471*

0.033

d

0.120**

0.229**

0.373**

0.027

0.537

1.740

−0.164

−1.249**

−0.008

−0.002

−0.026

−0.284**

−0.639

1.167**

−1.318**

0.092

α

−0.062

−0.066

−0.208**

−0.005

0.094

1.819

0.111

0.080

0.000

0.004

0.092

0.053

−0.111

−0.122

0.092

−0.006

rs41919984

a

0.009

−0.036

0.048

−0.010

−0.308

−0.003

0.011

0.463*

−0.012

−0.005

−0.121

0.027

0.292

−0.323

0.445*

−0.030

d

0.138**

0.258**

0.409**

0.027

0.559

−0.059

−0.233

−1.333**

0.012

−0.003

−0.042

−0.268**

−0.577

1.183**

−1.372**

0.095*

α

0.067*

0.073

0.220**

0.001

−0.072

−0.028

−0.087

−0.100

−0.006

−0.006

−0.138

−0.086

0.049

0.176

−0.135

0.010

rs41919985

a

0.020

−0.020

0.087

−0.009

−0.305

0.000

−0.045

0.421*

−0.004

−0.006

−0.130

0.033

0.366

−0.302

0.415

−0.029

d

0.125**

0.239**

0.361**

0.025

0.560

−0.063

−0.162

−1.290**

0.003

−0.001

−0.030

−0.278**

−0.677

1.164**

−1.344**

0.094*

α

−0.032

−0.120

−0.064

−0.019

−0.539

0.026

0.022

0.962**

−0.005

−0.005

−0.117

0.150

0.650

−0.790*

0.978**

−0.068

rs41919986

a

−0.025

0.020

−0.073

0.006

0.293

−0.006

0.068

−0.415*

−0.001

0.004

0.092

−0.050

−0.414

0.318

−0.425

0.029

d

0.122**

0.224**

0.350**

0.024

0.563

−0.072

−0.106

−1.301**

−0.017

−0.004

−0.032

−0.301**

−0.798

1.210**

−1.390**

0.097*

α

0.026

0.113

0.072

0.016

0.528

−0.036

0.024

−0.957**

−0.008

0.002

0.079

−0.176

−0.746

0.822*

−1.004**

0.070

  1. Note: a means additive effect; d means dominant effect; α means allele substitution effect. The asterisk (*) means the additive, dominant or allele substitution effect of the locus indicated differ at P < 0.05 and the asterisk (**) means the additive, dominant or allele substitution effect of the locus indicated differ at P < 0.01