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Fig. 6 | BMC Genetics

Fig. 6

From: Transmission of trisomy decreases with maternal age in mouse models of Down syndrome, mirroring a phenomenon in human Down syndrome mothers

Fig. 6

A gradual decrease in probability to transmit trisomy to offspring with maternal age is seen both in DS model mice and in DS women. a Maternal age in DS model mice was grouped into bins of 45 days. A gradual and similar decrease in the probability to transmit the trisomy with maternal age is seen for both Tc1 and Ts65Dn model mice. b Maternal age in human DS was grouped into 4 bins of 5 years groups. Similar to the mice, a gradual decrease in the probability to transmit trisomy with maternal age is evident

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