Fig. 6From: Transmission of trisomy decreases with maternal age in mouse models of Down syndrome, mirroring a phenomenon in human Down syndrome mothersA gradual decrease in probability to transmit trisomy to offspring with maternal age is seen both in DS model mice and in DS women. a Maternal age in DS model mice was grouped into bins of 45Â days. A gradual and similar decrease in the probability to transmit the trisomy with maternal age is seen for both Tc1 and Ts65Dn model mice. b Maternal age in human DS was grouped into 4 bins of 5Â years groups. Similar to the mice, a gradual decrease in the probability to transmit trisomy with maternal age is evidentBack to article page