Fig. 2From: Transmission of trisomy decreases with maternal age in mouse models of Down syndrome, mirroring a phenomenon in human Down syndrome mothersLitter size decreases with maternal age in DS model mice. Litter size of females younger than 200 days (n = 46) is ~ 2 fold higher than for females older than 200 days (n = 11, p = 0.0081). The analysis was performed only for litters where the genotype for the entire progeny is knownBack to article page