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Table 3 Multiple logistic regression results for the association of genetic ancestry with components of metabolic syndrome

From: Cardio-metabolic parameters are associated with genetic admixture estimates in a pediatric population from Colombia

Phenotype

Ancestry

OR (CI-95 %)a

P-Value a

OR (CI-95 %)b

P-Value b

OR (CI-98.3 %)c

BMI

European

1.01 (0.99–1.04)

0.314

1.02 (0.99–1.04)

0.207

1.01 (0.99–1.05)

African

0.99 (0.96–1.02)

0.556

0.98 (0.95–1.01)

0.317

0.98 (0.95–1.02)

Amerindian

1.35 (0.95–1.02)

0.426

0.99 (0.95–1.02)

0.511

0.99 (0.95–1.03)

WC

European

1.00 (0.94–1.06)

0.963

1.00 (0.94–1.07)

0.880

1.00 (0.93–1.09)

African

1.00 (0.93–1.07)

0.954

1.00 (0.93–1.07)

0.946

1.00 (0.91–1.09)

Amerindian

0.99 (0.91–1.08)

0.870

0.99 (0.90–1.08)

0.789

0.99 (0.89–1.10)

Fasting glucose

European

1.00 (0.93–1.08)

0.938

1.03 (0.96–1.11)

0.441

1.03 (0.94–1.13)

African

1.04 (0.97–1.12)

0.217

1.02 (0.95–1.10)

0.532

1.02 (0.94–1.11)

Amerindian

0.92 (0.82–1.02)

0.112

0.90 (0.81–1.00)

0.062

0.90 (0.79–1.03)

Fasting insulin

European

0.98 (0.94–1.03)

0.484

0.97 (0.92–1.03)

0.367

0.97 (0.91–1.04)

African

1.03 (0.98–1.08)

0.234

1.05 (0.99–1.11)

0.119

1.05 (0.97–1.13)

Amerindian

0.99 (0.92–1.05)

0.671

0.98 (0.91–1.06)

0.599

0.98 (0.89–1.07)

HOMA score

European

0.98 (0.93–1.03)

0.340

0.97 (0.91–1.03)

0.299

0.97 (0.90–1.04)

African

1.03 (0.98–1.09)

0.201

1.05 (0.99–1.12)

0.109

1.05 (0.97–1.14)

Amerindian

0.99 (0.92–1.07)

0.869

0.98 (0.91–1.07)

0.698

0.98 (0.89–1.09)

TG

European

0.98 (0.95–1.00)

0.049

0.98 (0.95–1.01)

0.120

0.98 (0.95–1.01)

African

0.99 (0.96–1.02)

0.661

0.98 (0.95–1.02)

0.369

0.98 (0.95–1.02

Amerindian

1.06 (1.02–1.09)

0.002

1.06 (1.02–1.10)

0.002

1.06 (1.01–1.11)

HDL

European

1.00 (0.97–1.03)

0.890

1.00 (0.96–1.03)

0.843

1.00 (0.96–1.04)

African

1.00 (0.96–1.03)

0.905

1.00 (0.96–1.04)

0.956

1.00 (0.95–1.05)

Amerindian

1.01 (0.97–1.05)

0.610

1.01 (0.97–1.06)

0.573

1.01 (0.96–1.07)

SBP

European

0.93 (0.88–0.97)

0.003

0.93 (0.88–0.99)

0.008

0.93 (0.87–0.99)

African

1.08 (1.03–1.13)

0.002

1.07 (1.02–1.13)

0.008

1.07 (1.01–1.14)

Amerindian

1.01 (0.94–1.09)

0.706

1.01 (0.94–1.09)

0.728

1.01 (0.92–1.11)

DBP

European

0.98 (0.94–1.02)

0.399

0.98 (0.94–1.03)

0.433

0.98 (0.93–1.04)

African

0.98 (0.93–1.04)

0.538

0.98 (0.92–1.04)

0.504

0.98 (0.91–1.05)

Amerindian

1.05 (0.99–1.12)

0.078

1.06 (0.99–1.12)

0.078

1.06 (0.98–1.14)

  1. aUnivariate analysis
  2. bAll models have been adjusted for gender, age, pubertal maturation, socioeconomic stratum, physical activity, percent of calories from simple carbohydrate and consumption of fruits daily. The models for WC, fasting glucose, fasting insulin, HOMA score, TG, HDL, DBP and SBP have also been adjusted for BMI. The significant p values (P< 0.05) are given in bold. The comparison was statistically significant according to the prespecified Bonferroni-corrected threshold of P <0.0167, but not for the global correction P <0.0018
  3. c 98.3 % Confidence Intervals (CI) are presented to be consistent with a Bonferroni correction
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BMC Genomic Data

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