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Table 6 BMI-associated SNPs in ERBB4 in MESA and WHI African Americans

From: Multiethnic genome-wide association study identifies ethnic-specific associations with body mass index in Hispanics and African Americans

  MESA African Americans WHI African Americans
SNP Bp Minor Allele Model beta (95 % CI) p beta (95 % CI) p
rs6435678 212,418,713 C Unadjusted 1.106 (0.647, 1.565) 2.58 × 10−06 0.350 (0.098, 0.602) 0.006
+ PC 1 and 2 1.012 (0.526, 1.498) 4.71 × 10−05 0.238 (−0.014, 0.489) 0.064
+ age and sexa 1.121 (0.652, 1.591) 3.10 × 10−06 0.249 (−0.001, 0.500) 0.051
Full modela,b 1.104 (0.643, 1.564) 2.85 × 10−06 0.232 (−0.009, 0.476) 0.061
rs16847102 212,431,233 A Unadjusted 0.938 (0.458, 1.418) 1.33 × 10−04 0.349 (0.100, 0.599) 0.006
+ PC 1 and 2 0.911 (0.430, 1.393) 2.15 × 10−04 0.238 (−0.012, 0.487) 0.062
+ age and sexa 1.041 (0.576, 1.506) 1.25 × 10−05 0.245 (−0.003, 0.493) 0.053
Full modela,b 1.026 (0.570,1.483) 1.12 × 10−05 0.219 (−0.021, 0.460) 0.074
  1. Abbreviations: Bp base pair, CI Confidence Interval, PC principal components
  2. a Only the MESA analyses are sex-adjusted
  3. b Full model includes all ethnic-specific model covariates