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Fig. 2 | BMC Genetics

Fig. 2

From: Allelic imbalance of multiple sclerosis susceptibility genes IKZF3 and IQGAP1 in human peripheral blood

Fig. 2

Samples from homozygous carriers of the risk allele at rs11609 display higher IQGAP1 expression. Expression of IKZF3 and IQGAP1 relative to 18S rRNA in samples from MS patients genotyped for (a) rs907091 in IKZF3 (TT (risk): n = 28; CC (protective): n = 44) and (b) rs11609 IQGAP1 (CC (risk): n = 23; GG (protective): n = 36). Samples from individuals homozygous for the risk allele were compared with samples from individuals homozygous for the protective allele with two-tailed Mann-Whitney U-test. P-values <0.05 were considered significant, only the significant p-value is provided in the graph

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