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Table 2 Interaction between PA and FTO SNPs on adiposity-related phenotype

From: Physical activity and FTO genotype by physical activity interactive influences on obesity

SNP rs no. Phenotype Major/major Major/minor Minor/minor Pa
PA_Yes PA_No PA_Yes PA_No PA_Yes PA_No
rs3751812 (G/T) BMI 27.8 ± 6.1 28.9 ± 6.4 28.2 ± 5.7 31.2 ± 7.1 30.9 ± 4.8 37.3 ± 8.3 0.08
Fat mass 20.2 ± 10.9 24.2 ± 11.6 21.1 ± 9.7 27.5 ± 12.8 26.3 ± 8.5 38.4 ± 16.5 0.12
HC 104.2 ± 12.7 106.5 ± 13.3 105.5 ± 11.5 110.9 ± 13.7 111.2 ± 9.8 122.7 ± 16.1 0.13
WC 92.7 ± 15.3 96.5 ± 16.3 94.2 ± 14.7 100.4 ± 16.1 102.5 ± 13.3 111.5 ± 19.4 0.46
rs8050136 (C/A) BMI 28.0 ± 6.1 28.9 ± 6.5 27.9 ± 5.7 30.9 ± 7.0 30.7 ± 4.9 34.7 ± 9.0 0.14
Fat mass 20.5 ± 11.0 24.4 ± 11.8 20.6 ± 9.7 27.1 ± 12.6 25.4 ± 8.6 33.2 ± 17.4 0.10
HC 104.6 ± 12.5 106.6 ± 13.4 104.8 ± 12.0 110.4 ± 13.7 109.9 ± 10.0 118.3 ± 16.8 0.14
WC 92.9 ± 15.2 96.8 ± 16.6 93.8 ± 14.9 100.0 ± 15.9 100.7 ± 14.3 105.8 ± 20.8 0.61
rs9939609 (T/A) BMI 27.9 ± 6.2 28.8 ± 6.4 28.0 ± 5.7 30.9 ± 7.0 30.6 ± 4.8 34.7 ± 9.0 0.60
Fat mass 20.4 ± 11.1 24.3 ± 11.8 20.8 ± 9.6 27.1 ± 11.8 25.3 ± 8.4 33.2 ± 17.4 0.17
HC 104.4 ± 12.8 106.4 ± 13.2 105.0 ± 11.7 110.3 ± 13.6 109.9 ± 9.7 118.3 ± 16.8 0.21
WC 92.7 ± 15.5 96.6 ± 16.6 94.1 ± 14.6 100.0 ± 15.8 100.2 ± 14.1 105.8 ± 20.8 0.78
  1. Data are mean ± SD unless otherwise indicated. SNP rs no (Major allele/Minor allele) and bold allele indicates risk allele; BMI, body mass index; HC, hip circumference; WC, waist circumference. rs3751812 (major allele [G]; minor allele [T]); rs8050136 (major allele [C]; minor allele [A]); rs9939609 (major allele [T]; minor allele [A])
  2. aP-values from the genetic analyses regarding the significance of the intercation terms