Physical activity and FTO genotype by physical activity interactive influences on obesity

BMC Genomic Data

Table 2 Interaction between PA and FTO SNPs on adiposity-related phenotype

SNP rs no.	Phenotype	Major/major		Major/minor		Minor/minor		P^a
SNP rs no.	Phenotype	PA_Yes	PA_No	PA_Yes	PA_No	PA_Yes	PA_No	P^a
rs3751812 (G/T)	BMI	27.8 ± 6.1	28.9 ± 6.4	28.2 ± 5.7	31.2 ± 7.1	30.9 ± 4.8	37.3 ± 8.3	0.08
	Fat mass	20.2 ± 10.9	24.2 ± 11.6	21.1 ± 9.7	27.5 ± 12.8	26.3 ± 8.5	38.4 ± 16.5	0.12
	HC	104.2 ± 12.7	106.5 ± 13.3	105.5 ± 11.5	110.9 ± 13.7	111.2 ± 9.8	122.7 ± 16.1	0.13
	WC	92.7 ± 15.3	96.5 ± 16.3	94.2 ± 14.7	100.4 ± 16.1	102.5 ± 13.3	111.5 ± 19.4	0.46
rs8050136 (C/A)	BMI	28.0 ± 6.1	28.9 ± 6.5	27.9 ± 5.7	30.9 ± 7.0	30.7 ± 4.9	34.7 ± 9.0	0.14
	Fat mass	20.5 ± 11.0	24.4 ± 11.8	20.6 ± 9.7	27.1 ± 12.6	25.4 ± 8.6	33.2 ± 17.4	0.10
	HC	104.6 ± 12.5	106.6 ± 13.4	104.8 ± 12.0	110.4 ± 13.7	109.9 ± 10.0	118.3 ± 16.8	0.14
	WC	92.9 ± 15.2	96.8 ± 16.6	93.8 ± 14.9	100.0 ± 15.9	100.7 ± 14.3	105.8 ± 20.8	0.61
rs9939609 (T/A)	BMI	27.9 ± 6.2	28.8 ± 6.4	28.0 ± 5.7	30.9 ± 7.0	30.6 ± 4.8	34.7 ± 9.0	0.60
	Fat mass	20.4 ± 11.1	24.3 ± 11.8	20.8 ± 9.6	27.1 ± 11.8	25.3 ± 8.4	33.2 ± 17.4	0.17
	HC	104.4 ± 12.8	106.4 ± 13.2	105.0 ± 11.7	110.3 ± 13.6	109.9 ± 9.7	118.3 ± 16.8	0.21
	WC	92.7 ± 15.5	96.6 ± 16.6	94.1 ± 14.6	100.0 ± 15.8	100.2 ± 14.1	105.8 ± 20.8	0.78

Data are mean ± SD unless otherwise indicated. SNP rs no (Major allele/Minor allele) and bold allele indicates risk allele; BMI, body mass index; HC, hip circumference; WC, waist circumference. rs3751812 (major allele [G]; minor allele [T]); rs8050136 (major allele [C]; minor allele [A]); rs9939609 (major allele [T]; minor allele [A])
^aP-values from the genetic analyses regarding the significance of the intercation terms

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