From: MAPK1/ERK2 as novel target genes for pain in head and neck cancer patients
Canonical pathways | p values | Ratio |
---|---|---|
Airway Inflammation in Asthma | 3.02E-08 | 75.0Â % |
Differential Regulation of Cytokine Production in Macrophages and T Helper Cells by IL-17A and IL-17Â F | 2.09E-10 | 27.8Â % |
Differential Regulation of Cytokine Production in Intestinal Epithelial Cells by IL-17A and IL-17Â F | 8.13E-10 | 21.7Â % |
TNFR2 Signaling | 2.34E-09 | 17.9Â % |
Role of Cytokines in Mediating Communication between Immune Cells | 6.31E-16 | 17.3Â % |
IL-10 Signaling | 7.94E-17 | 14.7Â % |
Role of Hypercytokinemia/hyperchemokinemia in the Pathogenesis of Influenza | 1.82E-10 | 14.6Â % |
T Helper Cell Differentiation | 6.31E-13 | 11.9Â % |
Graft-versus-Host Disease Signaling | 2.51E-08 | 11.4Â % |
Altered T Cell and B Cell Signaling in Rheumatoid Arthritis | 3.98E-14 | 11.1Â % |
IL-6 Signaling | 3.16E-18 | 10.3Â % |
Hepatic Cholestasis | 3.16E-24 | 10.1Â % |
PPAR Signaling | 1.26E-13 | 10.0Â % |
Activation of IRF by Cytosolic Pattern Recognition Receptors | 1.95E-09 | 10.0Â % |
Role of PKR in Interferon Induction and Antiviral Response | 1.20E-06 | 10.0Â % |
Communication between Innate and Adaptive Immune Cells | 3.98E-12 | 9.8Â % |
Role of IL-17Â F in Allergic Inflammatory Airway Diseases | 1.32E-06 | 9.8Â % |
HMGB1 Signaling | 3.16E-16 | 9.3Â % |
Hematopoiesis from Pluripotent Stem Cells | 1.78E-06 | 9.1Â % |
TREM1 Signaling | 4.68E-09 | 8.7Â % |
Role of Pattern Recognition Receptors in Recognition of Bacteria and Viruses | 2.51E-14 | 8.4Â % |
Allograft Rejection Signaling | 2.51E-06 | 8.3Â % |
Crosstalk between Dendritic Cells and Natural Killer Cells | 4.37E-10 | 7.9Â % |
CD40 Signaling | 1.74E-07 | 7.8Â % |
Type I Diabetes Mellitus Signaling | 3.16E-11 | 7.6Â % |
IL-15 Signaling | 2.00E-07 | 7.6Â % |
LXR/RXR Activation | 1.58E-12 | 7.4Â % |
Role of IL-17A in Arthritis | 4.07E-06 | 7.4Â % |
Toll-like Receptor Signaling | 3.09E-07 | 6.9Â % |
Induction of Apoptosis by HIV1 | 5.75E-06 | 6.8Â % |
PXR/RXR Activation | 7.59E-06 | 6.4Â % |
Hepatic Fibrosis/Hepatic Stellate Cell Activation | 2.00E-15 | 6.1Â % |
Atherosclerosis Signaling | 3.63E-09 | 5.8Â % |
Role of Osteoblasts, Osteoclasts and Chondrocytes in Rheumatoid Arthritis | 6.31E-15 | 5.6Â % |
Dendritic Cell Maturation | 3.98E-11 | 5.3Â % |
NF-κB Signaling | 3.98E-11 | 5.3 % |
p38 MAPK Signaling | 1.12E-07 | 5.1Â % |
Glucocorticoid Receptor Signaling | 1.26E-15 | 5.0Â % |
Acute Phase Response Signaling | 1.20E-09 | 4.8Â % |
LPS/IL-1 Mediated Inhibition of RXR Function | 2.29E-10 | 4.3Â % |
Role of Macrophages, Fibroblasts and Endothelial Cells in Rheumatoid Arthritis | 2.00E-13 | 4.2Â % |
Granulocyte Adhesion and Diapedesis | 3.31E-08 | 4.2Â % |
FXR/RXR Activation | 4.90E-06 | 4.0Â % |
IL-12 Signaling and Production in Macrophages | 6.17E-06 | 3.8Â % |
PPARα/RXRα Activation | 8.71E-07 | 3.6 % |
Production of Nitric Oxide and Reactive Oxygen Species in Macrophages | 1.38E-06 | 3.4Â % |