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Table 3 The power of max_PC for various tests based on simulations with global significance at p ≤ α (0.05) in an admixture population

From: Testing association and maternally mediated genetic effects with the principal component analysis in case-parents studies

Test Association Maternally mediated genetic effects Association and maternally mediated genetic effects
N = 100 max_PC max_Z2 max_PC max_Z2 max_PC max_Z2 a max_Z2 b
 R1 = R2 = 2 0.602 0.600 0.564 0.561 0.803 0.787 0.562
 R1 = 1, R2 = 2 0.587 0.576 0.551 0.548 0.788 0.769 0.547
N = 200        
 R1 = R2 = 2 0.805 0.806 0.709 0.711 0.855 0.850 0.712
 R1 = 1, R2 = 2 0.779 0.783 0.682 0.683 0.834 0.826 0.684
N = 400        
 R1 = R2 = 2 0.878 0.879 0.800 0.798 0.882 0.875 0.796
 R1 = 1, R2 = 2 0.864 0.867 0.776 0.777 0.879 0.870 0.769
  1. aThe max_Z2 using 2C − F − M
  2. bThe max_Z2 using M − F