Testing association and maternally mediated genetic effects with the principal component analysis in case-parents studies

Table 3 The power of max_PC for various tests based on simulations with global significance at p ≤ α (0.05) in an admixture population

Test	Association		Maternally mediated genetic effects		Association and maternally mediated genetic effects
N = 100	max_PC	max_Z²	max_PC	max_Z²	max_PC	max_Z^{2 a}	max_Z^{2 b}
R₁ = R₂ = 2	0.602	0.600	0.564	0.561	0.803	0.787	0.562
R₁ = 1, R₂ = 2	0.587	0.576	0.551	0.548	0.788	0.769	0.547
N = 200
R₁ = R₂ = 2	0.805	0.806	0.709	0.711	0.855	0.850	0.712
R₁ = 1, R₂ = 2	0.779	0.783	0.682	0.683	0.834	0.826	0.684
N = 400
R₁ = R₂ = 2	0.878	0.879	0.800	0.798	0.882	0.875	0.796
R₁ = 1, R₂ = 2	0.864	0.867	0.776	0.777	0.879	0.870	0.769

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