Skip to main content

Table 2 The powers of max_PC and max_Z2 for various tests based on simulations with global significance at p ≤ α (0.05) in a homogeneous population

From: Testing association and maternally mediated genetic effects with the principal component analysis in case-parents studies

Test Association Maternally mediated genetic effects Association and maternally mediated genetic effects
N = 100 max_PC max_Z2 max_PC max_Z2 max_PC max_Z2 a max_Z2 b
 R1 = R2 = 2 0.616 0.607 0.588 0.586 0.815 0.800 0.584
 R1 = 1, R2 = 2 0.600 0.582 0.579 0.581 0.808 0.787 0.582
N = 200        
 R1 = R2 = 2 0.819 0.820 0.725 0.711 0.917 0.902 0.713
 R1 = 1, R2 = 2 0.803 0.810 0.702 0.704 0.911 0.898 0.702
N = 400        
 R1 = R2 = 2 0.908 0.900 0.819 0.821 0.952 0.937 0.822
 R1 = 1, R2 = 2 0.875 0.874 0.807 0.809 0.926 0.915 0.810
  1. aThe max_Z2 using 2C − F − M
  2. bThe max_Z2 using M − F