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Table 2 QTLs with suggestive linkage for arterial stiffness in F2 (Dahl S x R)-intercross rats

From: Sex-specific genetic determinants for arterial stiffness in Dahl salt-sensitive hypertensive rats

Chr

Reference marker

Location (Mbp)

LOD

Trait

Males

5

SNP2790733

55.43

2.3

PWVaorta

20

SNP2803750

48.28

2.0

PWVaorta

Females

9

SNP2795465

30.75

2.8

PWVaorta

11

SNP2797258

23.12

2.1

PWVaorta

15

SNP2800195

50.59

2.1

PWVaorta

  1. QTL quantitative trait locus, Chr chromosome, PWV aorta Pulse Wave Velocity in aorta, LOD logarithm of the odds score derived from the likelihood ratio statistic using a factor of 4.6. For marker regression analysis significance was determined from 2000 permutations on data set: Highly significant LOD ≥ 4.3, Significant LOD ≥ 3.0and Suggestive linkage LOD ≥ 2.0. SNP locations on rat genome as per NCBI Rat Genome Assembly Annotation Release 105