Table 1 Longitudinal GAW19 statistical models, data set, and software used by this group
Contribution | Phenotype | Covariates | Genetic data | Data Set | Model(s) | Longitudinal correlation | Software |
|---|---|---|---|---|---|---|---|
Chiu et al. [10] | Hypertension status (Baseline, Longitudinal, Ever, Progression) | None | GWA chromosome 3 | Real | multipoint LD mapping using GEE | Independent working correlation | Author’s software in FORTRAN |
Justice et al. [11] | SBP adjusted for BP medication | Age, sex, PCs (1–4), (smoking nonsignificant) | GWA | Real | LCGM (phenotype) and VCs within mixed model (association) | Unstructured covariance | SAS (LCGM) MMAP (association) |
Melton et al. [12] | SBP | Age, sex, and smoking | WGS | Simulated | VC | Correlation between SBP responses | SOLAR |