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Table 1 Characteristics of COPDGene, ECLIPSE, and GenKOLS Subjects included in genome-wide association analysis. For continuous variables, the mean is given first followed by the standard deviation

From: A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry

 

COPDGene NHW

COPDGene AA

ECLIPSE

GenKOLS

Sample size (#COPD cases)

6659 (2812)

3260 (821)

1942 (1764)

1671 (863)

Gender (% male)

47.73 %

44.79 %

66.17 %

58.71 %

Age (years)

62.0 (8.9)

54.6 (7.2)

63.1 (7.6)

60.7 (11.1)

Height (cm)

169.7 (9.5)

171.0 (9.7)

169.7 (9.1)

170.8 (8.9)

BMI (kg/m2)

28.7 (6.0)

29.07 (6.7)

26.8 (5.5)

25.9 (4.6)

Pack-years

47.2 (26.0)

38.3 (21.6)

48.6 (27.7)

26.0 (17.4)

Current Smoking (%)

38.9 %

80.0 %

34.8 %

43.8 %

FEV1 (L)

2.20 (0.95)

2.30 (0.86)

1.50 (0.78)

2.38 (1.10)

FEV1 (% predicted)

74.0 (26.0)

82.0 (23.9)

53.1 (23.2)

72.2 (26.2)

FEV1/FVC

0.64 (0.17)

0.72 (0.14)

0.48 (0.15)

0.65 (0.17)

  1. Notes: FEV1, FEV1 (% predicted), and FEV1/FVC are all based on post-bronchodilator spirometry