Fig. 3

Characterization of the newly identified locus at 13q22.1. a Below the line representing base positions in Mb, different features were represented: the PC1 association signals (vertical dark violet lines), the |iHS| value for each SNP tested (vertical dark green), the 200 kb intervals defined as positively selected according to the iHS analysis (light green bars), the genomic intervals with evidence of positive selection from the literature (darker green bars) and RefSeq genes (black lines); b detail of the core region defined showing: RefSeq genes (black), UCSC genes (green), lincRNA transcripts (purple) and lincRNA RNAseq reads (blue scale) according to Cabili et al. 2011 [25], transcription levels and epigenetic features in NHEK cell line from the ENCODE project, the DNase hypersensitivity clusters from 125 ENCODE cell types