From: Iron and hepcidin as risk factors in atherosclerosis: what do the genes say?
 |  |  | Presence of plaque | IMT | ABI at rest | ABI after exercise | ||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
SNP – Tested allele | CHR:BP (Build 37) | Freq | H* | OR | 95 % CI | H* | Beta | 95 % CI | H* | Beta | 95 % CI | H* | Beta | 95 % CI |
Multi-SNP score | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
Q1 | Â | Â | Ref | Ref | Ref | Ref | Ref | Ref | Ref | Ref | Ref | Ref | Ref | Ref |
Q2 |  |  | >1 | 1.06 | 0.66; 1.71 | + | −0.024 | −0.051; 0.002 | - | 0.003 | −0.022; 0.028 | - | −0.024 | −0.051; 0.002 |
Q3 |  |  | >1 | 0.82 | 0.51; 1.34 | + | −0.007 | −0.034; 0.020 | - | 0.005 | −0.021; 0.030 | - | −0.007 | −0.034; 0.020 |
Q4 |  |  | >1 | 1.13 | 0.70; 1.82 | + | 0.009 | −0.018; 0.036 | - | 0.003 | −0.022; 0.028 | - | 0.009 | −0.018; 0.036 |
rs744653 – T | 2:190,378,750 | 0.86 | <1 | 1.10 | 0.78; 1.55 | - | −0.006 | −0.025; 0.014 | + | −0.013 | −0.031; 0.005 | + | −0.019 | −0.052; 0.014 |
rs8177240 – T†| 3:133,477,701 | 0.66 | ? | 1.13 | 0.87; 1.46 | ? | −0.010 | −0.025; 0.004 | ? | 0.014 | 0.000; 0.027 | ? | 0.030 | 0.005; 0.055 |
rs9990333 – T | 3:195,827,205 | 0.47 | >1 | 1.32 | 1.03; 1.68 | + | 0.012 | −0.002; 0.025 | - | 0.006 | −0.006; 0.019 | - | 0.016 | −0.007; 0.040 |
rs1800562 – A | 6: 26,093,141 | 0.06 | >1 | 1.03 | 0.62; 1.69 | + | −0.017 | −0.045; 0.011 | - | −0.006 | −0.032; 0.020 | - | −0.005 | −0.054; 0.043 |
rs1799945 – C | 6: 26,091,179 | 0.84 | <1 | 1.19 | 0.86; 1.64 | - | 0.011 | −0.007; 0.029 | + | 0.003 | −0.014; 0.019 | + | −0.006 | −0.037; 0.024 |
rs7385804 – A | 7: 100,235,970 | 0.64 | >1 | 0.92 | 0.72; 1.18 | + | −0.006 | −0.020; 0.008 | - | 0.000 | −0.013; 0.013 | - | 0.018 | −0.006; 0.042 |
rs4921915 – A‡ | 8: 18,272,466 | 0.78 | ? | 1.42 | 1.04; 1.92 | ? | −0.006 | −0.023; 0.010 | ? | 0.002 | −0.014; 0.017 | ? | 0.005 | −0.023; 0.034 |
rs651007 – T | 9: 136,153,875 | 0.20 | <1 | 0.84 | 0.62; 1.15 | - | −0.021 | −0.038; 0.004 | + | 0.003 | −0.013; 0.019 | + | 0.034 | 0.004; 0.063 |
rs6486121 – T‡ | 11: 13,355,770 | 0.64 | ? | 0.94 | 0.73; 1.20 | ? | 0.012 | −0.002; 0.026 | ? | −0.004 | −0.017; 0.009 | ? | −0.007 | −0.031; 0.018 |
rs174577 – A‡ | 11: 61,604,814 | 0.32 | ? | 1.10 | 0.85; 1.42 | ? | 0.001 | −0.013; 0.015 | ? | 0.004 | −0.009; 0.017 | ? | 0.015 | −0.009; 0.040 |
rs411988 – A | 17: 56,709,034 | 0.58 | <1 | 0.92 | 0.73;1.17 | - | −0.001 | −0.015; 0.012 | + | 0.004 | −0.008; 0.017 | + | −0.010 | −0.033; 0.013 |
rs855791 – A | 22: 37,462,936 | 0.46 | <1 | 1.20 | 0.94; 1.54 | - | −0.010 | −0.023; 0.004 | + | 0.005 | −0.008; 0.018 | + | 0.010 | −0.013; 0.034 |