| |
Most strongly associated SNP in discovery
|
Most strongly associated SNP in validation
| |
---|
BTCa
|
Interval (Mbp)b
|
SNP
|
Position (bp)
|
-log10 (P)
|
Effect ± SE
|
MAFc
|
\( \frac{\sigma_d^2}{\sigma_p^2} \) (%)d
|
SNP
|
Position (bp)
|
-log10 (P)
|
Effect ± SE
|
MAF
|
\( \frac{\sigma_d^2}{\sigma_p^2} \) (%)
|
Genese
|
---|
1
|
19.667 - 19.777
|
rs110080440
|
19706636
|
4.651
|
−3.802 ± 0.896
|
0.299
|
0.091
|
rs109600947
|
19776964
|
2.178
|
−4.129 ± 1.52
|
0.249
|
0.080
|
NA
|
2
|
80.202 - 80.654
|
rs41591067
|
80201648
|
4.412
|
3.07 ± 0.746
|
0.500
|
0.084
|
rs133868000
|
80276795
|
2.403
|
−3.268 ± 1.133
|
0.473
|
0.089
|
MYO1B
f
|
3
|
15.808 - 15.963
|
rs134910746
|
15947344
|
4.119
|
3.024 ± 0.764
|
0.420
|
0.078
|
rs29020504
|
15808470
|
2.505
|
−5.434 ± 1.837
|
0.197
|
0.099
|
KCNN3
|
7
|
62.509 - 62.852
|
rs29013244
|
62508803
|
4.252
|
3.012 ± 0.747
|
0.480
|
0.081
|
rs43520270
|
62851917
|
2.123
|
3.664 ± 1.37
|
0.304
|
0.081
|
ABLIM3
|
23
|
46.082 - 46.581
|
rs137262994
|
46579868
|
4.494
|
−3.234 ± 0.777
|
0.407
|
0.087
|
rs109881533
|
46081778
|
2.401
|
4.222 ± 1.464
|
0.264
|
0.090
|
OFCC1
|
23
|
50.929 - 51.326
|
rs110165999
|
51326222
|
5.087
|
−5.153 ± 1.154
|
0.205
|
0.101
|
rs134147379
|
51081072
|
2.212
|
−3.689 ± 1.345
|
0.309
|
0.083
|
GMDS
|
25
|
39.070 - 39.921
|
rs135893130
|
39548382
|
4.364
|
−3.225 ± 0.788
|
0.390
|
0.084
|
rs108968775
|
39070284
|
2.808
|
3.583 ± 1.131
|
0.489
|
0.108
|
LOC618542
|
28
|
43.832 - 44.145
|
rs133899460
|
44144815
|
4.032
|
−2.918 ± 0.7461
|
0.480
|
0.076
|
rs109392728
|
43831664
|
2.404
|
−6.638 ± 2.302
|
0.143
|
0.089
|
CHAT
|
-
a
BTC Bos Taurus chromosome
-
bIntervals containing individually validated SNPs are in bold
-
c
MAF minor allele frequency
-
d
σ
2
d
= dominance variance; σ
2
p
= phenotypic variance
-
eGenes with both top SNPs in discovery and validation inside them are in bold
-
fGenes with individually validated SNPs within them