Table 2 Allele and genotype frequencies of the IL10 and TNFα gene promoter regions. Data from our study and HapMap CEU population
Gene | Polymorphism | Allele and genotype frequencies | ||||
|---|---|---|---|---|---|---|
| Â | Â | (HAPMAP CEU allele and genotype frequencies data) | ||||
TNFα | −308 G > A (rs1800629) | G | A | GG | GA | AA |
| Â | Â | 0.900 | 0.100 | 0.83 | 0.14 | 0.03 |
| Â | Â | (0.827) | (0.173) | (0.877) | (0.123) | (0) |
IL10 | −1082 A > G (rs1800896) | A | G | AA | GA | GG |
| Â | Â | 0.415 | 0.585 | 0.20 | 0.43 | 0.37 |
| Â | Â | (0.469) | (0.531) | (0.212) | (0.513) | (0.274) |
|  | −819 T > C (rs1800871) | T | C | CC | CT | TT |
| Â | Â | 0.255 | 0.745 | 0.58 | 0.33 | 0.09 |
| Â | Â | (0.179) | (0.821) | (0.661) | (0.321) | (0.018) |
|  | −592 A > C (rs1800872) | C | A | CC | AC | AA |
| Â | Â | 0.720 | 0.280 | 0.54 | 0.36 | 0.10 |
| Â | Â | (0.788) | (0.212) | (0.628) | (0.319) | (0.053) |