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Table 1 Involvement of CAV1 epigenetic modification in cancers

From: Epigenetic modifications of caveolae associated proteins in health and disease

Cancer types

Promoter hypermethylation

Histone modification

CAV1 expression

Changes in physiology and pathophysiology

Breast

[55]

[59]

Down-regulated

Decreased migration after 5-AZA and TSA treatment [59]

[57]

[43]

[56]

[59]

[58]

Prostate

[62]

 

Down-regulated

Not described

 

[64]

   
 

[63]

   

Bladder

[68]

 

Down-regulated

Not described

Ovarian

[71]

[71]

Down-regulated

Over-expression of CAV1, reduced colony formation and increased apoptosis in ovarian cancer cell line [71]

Lung

[70]

 

Down-regulated

Over-expression of CAV1, reduced colony formation in lung cancer cell line [70]

Colorectal

[72]

 

Down-regulated

Not described

[73]

[74]

Liver

[75]

 

Down-regulated

Not described

[77]