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Table 4 Association between Index SNPs at TRPM6 and Serum Magnesium by Fasting Insulin Levels in ARIC European and African Americans

From: Genetic loci for serum magnesium among African-Americans and gene-environment interaction at MUC1 and TRPM6 in European-Americans: the Atherosclerosis Risk in Communities (ARIC) study

  N Beta (mmol/L) SE P-Value Variance explained P for interaction
European-Americans (rs11144134 T allele, frequency 0.92)    
Fasting insulin < 80pmol/L 5937 −0.013 0.002 1.6E-07 0.44 % 0.03
Fasting insulin ≥ 80pmol/L 2752 −0.008 0.003 1.8E-02 0.19 %  
African-Americans (rs113607577 G allele, frequency 0.90)    
Fasting insulin < 80pmol/L 1186 −0.026 0.006 3.5E-06 1.55 % 0.24
Fasting insulin ≥ 80pmol/L 1302 −0.014 0.005 9.0E-03 0.58 %