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Table 3 QTL regions for the daily feed intake and average daily weight trajectory parameters

From: Genome-wide association study on legendre random regression coefficients for the growth and feed intake trajectory on Duroc Boars

Trait

Coefficient

SSR1

Region1 (Start – End)

Reference SNP ID number

Location1 SNP with largest Impact2

Candidate gene (Gene Start - Stop)1

Function

Daily Feed Intake

Intercept

3

104.93 – 106.74

rs81374365

105,694,951

  

6

50.80 – 53.37

rs80971368

51,843,873

SIGLEC-5 (51.50 – 51.83)

Host Immune Response

7

8.39 – 9.65

rs80858822

9,162,386

EDN1 (9.15 – 9.16)

Vasoconstriction & Kidney Functions

8

30.60 – 31.03

rs81399022

30,934,915

TBC1D1 (31.01 – 31.05)

Energy Homoestasis

9

8.78 – 9.38

rs331988332

8,950,525

UCP2 (9.15 – 9.16) UCP3 (9.17 – 9.18)

Energy Homoestasis

9

65.35 – 66.81

rs81412363

66,001,271

  

9

146.99 – 147.55

rs81344419

147,145,126

  

11

78.00 – 78.81

rs81431902

78,262,842

TPP2 (78.24 – 78.32)

Anti-Satiety & Adipogenesis

14

16.41 – 17.22

rs80800316

16,678,119

GLRA3 (16.70 – 16.78)

Behavior

15

131.44 – 132.17

rs81454578

131,788,807

IGFBP5 (131.68 – 131.68)

Glucose Homeostasis

Linear

2

124.53 – 125.09

rs81474570

124,815,799

CDO1 (124.82 – 124.83)

Cysteine homeostasis

3

138.21 – 140.07

rs81336457

138,955,525

  

4

37.09 – 37.74

rs80849862

37,210,968

AZIN1 (37.09 – 37.74)

Polyamine Synthesis Regulation

Quadratic

1

25.01 – 27.47

rs80803840

25,469,368

GPR126 (25.29 – 25.41)

Cell Signaling

Average Daily Body Weight

Intercept

1

176.19 – 177.76

rs80837663

176,186,716

PHLPP1 (176.12 – 176.23) MC4R (178.55 – 178.56)

Insulin Signaling Regulation of Metabolism

4

44.24 – 46.14

rs80840184

44,687,188

NDUFAF6 (44.87 – 44.91)

Energy Homoestasis

7

125.06 – 125.99

rs80927576

125,383,498

VRK1 (125.27 – 125.31)

Cell Growth & Division

9

65.08 – 65.86

rs81412302

65,728,425

  

11

9.07 – 9.61

rs80786591

9,216,774

  

15

23.81 – 26.38

rs81451849

24,623,255

  

Linear

5

84.01 – 84.74

rs81325400

84,361,428

STAB2 (84.23 – 84.26)

Clearing of Metabolic Waste

Quadratic

1

17.42 – 18.35

rs80807545

17,637,973

  

4

82.08 – 82.89

rs80787131

82,154,248

IMPAD1 (82.11 – 82.13)

Formation of Skeletal Elements

6

100.55 – 106.32

rs81316981

100,548,492

CABLES1 (100.63 – 100.80)

Regulator of Cell Proliferation

12

52.69 – 53.31

rs81327396

53,063,765

  

15

9.03 – 10.57

rs80840353

10,127,793

KYNU (9.03 – 10.57)

Tryptophan Metabolism

  1. 1Location of SNP in megabases based on swine genome build 10.2
  2. 2The impact of a particular SNP within a given regions was determine by calculating the SNP variance (2pq (SNP Effect)2)