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Table 3 Allelic odds ratios for subtype of CRC in the Korean Cancer Prevention Study II sub-cohort

From: A colorectal cancer prediction model using traditional and genetic risk scores in Koreans

 

Reference number in Additional file 2 : Table S1

   

Colorectal cancer

Colon cancer

Rectal cancer

SNPs*

Chr.

RA

RAF

OR (95% CI)

OR (95% CI)

OR (95% CI)

rs3802842

4,7,19,29,32,34, 36

11

C

0.40

1.46 (1.14-1.86)

1.30 (0.93-1.81)

1.50 (1.10-2.04)

rs4444235

4,7,32,38

14

C

0.52

1.02 (0.80-1.29)

1.01 (0.73-1.40)

1.03 (0.76-1.40)

rs4939827

7,10,29,30,34,41,42,43,44,45,46

18

T

0.22

1.32 (1.01-1.71)

1.04 (0.71-1.52)

1.55 (1.11-2.16)

rs6983267

7,16,17,18,19,20,21,22,23,24,25,26,27,28

8

G

0.43

1.14 (0.91-1.43)

0.85 (0.61-1.17)

1.46 (1.08-1.97)

rs10505477

11,12,13,14,15

8

G

0.43

1.15 (0.92-1.45)

0.88 (0.64-1.21)

1.44 (1.06-1.94)

rs10795668

7,20,30,31,32,33,34

10

G

0.64

1.20 (0.92-1.55)

0.93 (0.66-1.32)

1.45 (1.03-2.05)

rs11169552

1

12

T

0.34

0.98 (0.76-1.25)

1.05 (0.75-1.47)

0.93 (0.67-1.28)

rs6687758

1,2

1

G

0.29

0.96 (0.74-1.25)

1.14 (0.80-1.63)

0.85 (0.60-1.20)

rs7014346

29

8

G

0.69

0.94 (0.73-1.21)

1.08 (0.76-1.54)

0.86 (0.62-1.18)

rs11903757

3

2

T

0.96

0.79 (0.45-1.42)

0.75 (0.35-1.63)

0.91 (0.42-1.96)

rs3217810

3

12

C

0.95

0.98 (0.19-5.21)

0.44 (0.08-2.45)

NE

rs10411210

20,28

19

T

0.18

0.91 (0.66-1.25)

0.82 (0.52-1.30)

1.00 (0.67-1.50)

rs961253

4,7,11,19,20,34, 38,47

20

A

0.10

1.38 (0.97-1.97)

1.19 (0.72-1.98)

1.45 (0.93-2.26)

rs6691170

1,2,4

1

T

0.09

NE

  

rs9929218

20,21,31,38,40

16

A

0.15

1.21 (0.87-1.68)

1.16 (0.74-1.83)

1.20 (0.78-1.82)

rs10911251

3

1

C

0.46

1.01 (0.80-1.29)

0.80 (0.58-1.12)

1.22 (0.90-1.66)

rs7758229

10

6

T

0.22

1.06 (0.80-1.41)

0.91 (0.60-1.37)

1.20 (0.84-1.71)

rs59336

3

12

T

0.63

0.94 (0.73-1.20)

0.79 (0.57-1.12)

1.09 (0.79-1.52)

rs3217901

37

12

G

0.65

1.10 (0.87-1.39)

1.51 (1.08-2.11)

0.83 (0.61-1.12)

rs10936599

1,4,5,6,7,8

3

T

0.61

1.09 (0.87-1.38)

1.07 (0.77-1.48)

1.11 (0.81-1.50)

rs647161

9

5

C

0.69

0.95 (0.73-1.22)

0.72 (0.51-1.01)

1.25 (0.88-1.77)

rs7136702

1

12

T

0.53

1.08 (0.85-1.37)

1.10 (0.79-1.54)

1.02 (0.75-1.39)

rs4779584

4,19,20,30,32,33,36,39

15

T

0.84

0.97 (0.70-1.34)

0.91 (0.58-1.43)

1.02 (0.67-1.55)

  1. CRC: colorectal cancer, Chr.: chromosome, RA: risky allele, RAF: risky allele frequency, OR: odds ratio, CI: confidence interval, NE: not estimated due to small number, SNP with ORs in bold were selected for genetic risk score calculations.
  2. *List of references and detailed information were summarized in Additional file 2: Table S1.