From: A colorectal cancer prediction model using traditional and genetic risk scores in Koreans
KCPS-II cohort (Whole participants) | KCPS-II sub-cohort (Case-cohort design) | ||||||
---|---|---|---|---|---|---|---|
CRC | No CRC | P | CRC | No CRC | P | ||
N | 258 | 145,584 | 173 | 1,514 | |||
Age, year | 50.7 ± 10.5 | 41.1 ± 10.3 | <0.001 | 49.7 ± 10.9 | 40.1 ± 9.4 | <0.001 | |
Sex, % of female | 24.1 | 37.9 | <0.001 | 25.0 | 37.6 | 0.001 | |
Body mass index, kg/m2 | 24.3 ± 2.7 | 23.6 ± 3.2 | <0.001 | 24.3 ± 2.7 | 23.5 ± 3.2 | 0.001 | |
Fasting blood glucose, mg/dL | 99.0 ± 25.3 | 91.0 ± 19.0 | <0.001 | 98.2 ± 27.8 | 90.1 ± 17.9 | <0.001 | |
Total cholesterol, mg/dL | 197.7 ± 37.1 | 189.0 ± 33.8 | 0.002 | 195.6 ± 36.9 | 189.3 ± 41.8 | 0.037 | |
Systolic blood pressure, mmHg | 123.4 ± 16.3 | 117.9 ± 14.4 | <0.001 | 121.8 ± 14.7 | 117.6 ± 14.3 | 0.037 | |
Smoking status, % | Ex | 31.0 | 17.7 | <0.001 | 29.6 | 15.8 | <0.001 |
Current | 29.9 | 29.2 | 30.7 | 30.2 | |||
Alcohol drinking (yes), % | 73.6 | 74.0 | 0.881 | 74.4 | 76.7 | 0.496 | |
Exercise (yes), % | 63.2 | 59.6 | 0.228 | 62.5 | 61.8 | 0.850 | |
Family history of CRC (yes), % | 5.0 | 2.3 | 0.005 | 5.1 | 2.0 | 0.011 |