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Table 1 Delta C q mean values and p-values for qPCR fragments 1 to 5

From: The nicotinic acetylcholine receptor alpha 4 subunit contains a functionally relevant SNP Haplotype

mRNA decay time difference

qPCR fragment

1

2

3

4

5

Δ C q mean

p-value

Δ C q mean

p-value

Δ C q mean

p-value

Δ C q mean

p-value

Δ C q mean

p-value

hap 1

hap 2

hap1/2

hap 1

hap 2

hap1/2

hap 1

hap 2

hap1/2

hap 1

hap 2

hap1/2

hap 1

hap 2

hap1/2

0 to 3 hrs

1.16

0.29

0.242

1.91

0.09

0.0291

1.61

0.26

0.066

1.07

-0.07

0.08

1.17

0.37

0.436

(-0.72 - 3.04)

(-1.57 -2.15)

 

(-0.31 -4.12)

(-1.77 -1.94)

 

(-0.73 -3.95)

(-1.61 -2.13)

 

(-0.70 -2.83)

(-1.66 -1.51)

 

(-1.48 -3.81)

(-1.73 -2.47)

 

0 to 6 hrs

2.54

1.95

0.403

3.34

2.41

0.313

3.04

2.48

0.546

2.23

1.7

0.503

3.69

3.34

0.821

(0.49-4.58)

(0.63-3.27)

 

(0.79-5.89)

(0.77-4.04)

 

(0.43-5.65)

(0.75-4.21)

 

(0.26-4.19)

(0.29-3.11)

 

(0.72-6.66)

(0.71-5.97)

 

0 to 24 hrs

5.74

5.64

0.918

6.18

6.24

0.952

5.06

4.77

0.778

5.21

4.77

0.679

8.16

10.73

0.0362

(3.86-7.62)

(3.22-8.06)

 

(4.02-8.33)

(3.84-8.63)

 

(2.79-7.34)

(2.55-7.00)

 

(3.55-6.87)

(2.23-7.32)

 

(5.42-10.90)

(6.03-13.44)

 
  1. Δ Cq mean, delta Cq mean: difference of the mean quantification cycle; confidence intervals are given in brackets.
  2. 1confidence interval for delta Cq-mean values of hap1 and hap2 are not significant.
  3. 2confidence interval for delta Cq-mean values of hap1 and hap2 are significant.
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BMC Genomic Data

ISSN: 2730-6844

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