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Table 3 Number of closed loop-motifs and their molecular components for each of the three reperfusion time points (0 h, 24 h, and 7d) following 1 h of ischemia

From: Regulatory networks in retinal ischemia-reperfusion injury

Closed loop-motifs

0 h

24 h

7d

Closed loop motifs

0

2681

699

mRNA

0

433

215

TFs

0

16

14

miRNA

0

53

34

  1. Only loop-motifs, which contained 3 statistically significantly and correlated pairings (miR-TF, miR-mRNA, and TF-mRNA) were listed here (p-value ≤ 0.05). It is noteworthy that although there were 43 differentially expressed molecular components at 0 h, there were insufficient numbers of statistically significant and correlated pairings at this initial time point.