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Table 1 Differentially expressed mRNAs, TFs and miRs at 0 h, 24 h, and 7d post-IR periods, filtered by fold change ≥ 2 and p-Value ≤ 0.05

From: Regulatory networks in retinal ischemia-reperfusion injury

Differentially expressed molecular components

0 h

24 h

7d

mRNA

31

919

678

TFs

2

45

39

miRs

10

66

63

  1. There were a total of 43 molecular components with altered expression at the 0 h reperfusion time point after a period of 1 h ischemia. This number increased significantly to 1030 by 24 h and then decreased to 780 by 7d in the post ischemic periods. There were fewer TFs than miRs or mRNAs across all time points, and there were fewer miRs than mRNAs across all time points, so that the number of TFs < miRs < mRNAs.