Skip to main content

Table 2 Burden analysis of CNV Regions reveals a higher number of CNVs in genes in individuals with narrow bipolar phenotype (BPI and BPII)

From: Copy number variants encompassing Mendelian disease genes in a large multigenerational family segregating bipolar disorder

  Unaffected Broad Narrow
No. All CNVs 28.1 28.7 29.5
P vs unaffected - 0.39 0.26
No. All CNVs in genes 15.6 16.8 17.3
P vs unaffected - 0.16 0.11
No. Rare CNVs in genes 9.7 11.0 11.3
P vs unaffected - 0.12 0.09
No. CNVs in disease genes 4.8 5.5 5.7
P vs unaffected - 0.11 0.06
No. Rare CNVs in disease genes 4.0 4.8 5.0
P vs unaffected - 0.07 0.06
  1. A trend towards an increased number of CNVs in disease genes in individuals with narrow bipolar phenotype is also reported.