Table 1 Summary of CNV calls for the Old Order Amish (n = 375) and controls (n = 1897)
| Â | Total | Deletions | Duplications | |||||||
|---|---|---|---|---|---|---|---|---|---|---|
Amish CNVs | Amish Inherited CNVs | Controls | Amish CNVs | Amish inherited CNVs | Controls | Amish CNVs | Amish inherited CNVs | Controls | ||
Total Number | All Samples | 18986 | 6345 | 77205 | 10942 | 4154 | 51138 | 8044 | 2191 | 26067 |
Affected | 3844 | 1380 | - | 2216 | 905 | - | 1628 | 475 | - | |
Unaffected | 12191 | 3962 | - | 6922 | 2581 | - | 5269 | 1381 | - | |
Average Size (bp) | All Samples | 36123 | 42064 | 29697 | 31124 | 32701 | 23768 | 42924 | 59815 | 41328 |
Affected | 41123 | 44572 | - | 39802 | 33575 | - | 42921 | 65523 | - | |
Unaffected | 34363 | 39932 | - | 29072 | 32093 | - | 41315 | 54581 | - | |
Burden (per individual) | All Samples | 50.6 | 23.2 | 40.7 | 29.2 | 15.2 | 27.0 | 21.6 | 8.2 | 13.7 |
Affected | 49.9 | 23.4 | - | 28.8 | 15.3 | - | 21.1 | 8.1 | - | |
Unaffected | 52.1 | 23.7 | - | 29.6 | 15.5 | - | 22.5 | 8.3 | - | |