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Table 6 Powers of SKAT under the assumption of two causal SNPs at the significance level of 0.05

From: An efficient weighted tag SNP-set analytical method in genome-wide association studies

Scenario

3

4

5

6

7

8

9

SKAT

0.16

0.1

0.265

0.508

0.13

0.123

0.674

SKAT-tag

0.207

0.1

0.334

0.539

0.132

0.114

0.637

Weighted SKAT

0.945

0.903

0.939

0.977

0.888

0.932

0.99

Weighted SKAT-tag

0.952

0.918

0.953

0.979

0.921

0.947

0.995