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Table 2 Simulation parameters in scenarios 2-9

From: An efficient weighted tag SNP-set analytical method in genome-wide association studies

Scenario

No. of causal SNP

Causal SNP

The position of causal SNP

Genotyped

MAF 1

Mean R 2 with the genotyped SNPs 2

2

1

Each of all the 34 SNPs

    

3

2

rs977003

46313002

Yes

0.449

0.0853

rs9534511

46366581

Yes

0.442

0.178

4

2

rs3803189

46306571

Yes

0.107

0.0474

rs977003

46313002

Yes

0.449

0.0853

5

2

rs3803189

46306571

Yes

0.107

0.0474

rs731779

46350039

Yes

0.161

0.2478

6

2

rs9526246

46347862

No

0.462

0.2164

rs9534511

46366581

Yes

0.442

0.178

7

2

rs3803189

46306571

Yes

0.107

0.0474

rs9526246

46347862

No

0.462

0.2164

8

2

rs3803189

46306571

Yes

0.107

0.0474

rs3742278

46317578

No

0.158

0.0535

9

2

rs6561333

46318313

No

0.466

0.1127

rs9526246

46347862

No

0.462

0.2164

  1. 1minor allele frequency.
  2. 2the average of R 2 between the causal SNP and 34 genotyped SNPs.