Common variants at the 9q22.33, 14q13.3 and ATM loci, and risk of differentiated thyroid cancer in the Cuban population

Table 1 Description of the five studied polymorphisms

Reference	Location	Chromosome	Polymorphism		Minor allele frequency in cases			Minor allele frequency in controls			Hardy-Weinberg equilibrium χ² p-value
			Allele change	Residue change	All	African origin	Others	All	African origin	Others	Cases	Controls
rs1801516	Coding region of ATM	11q22–23	G > A	D1853N	0.11	0.14	0.10	0.11	0.13	0.10	0.08	0.7
rs944289	Intergenic, 337 kb telomeric of NKX2–1	14q13.3	C > T	-	0.56	0.46	0.59	0.43	0.36	0.47	0.04	0.5
rs965513	Intergenic, 57 kb upstream to FOXE1	9q22.33	G > A	-	0.36	0.28	0.39	0.25	0.21	0.26	0.6	0.9
rs1867277	5′UTR of FOXE1	9q22.33	G > A	-	0.46	0.40	0.48	0.37	0.38	0.36	0.7	0.4
rs71369530	Exon 1 of FOXE1	9q22.33	-	Poly-alanine tract expansion	0.40	0.29	0.43	0.28	0.29	0.27	0.6	0.9

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