Pedigree of the family affected by atrial flutter
. Generation is indicated with roman numerals, and individual ID is indicated with Arabic numerals. Solid squares (males) and circles (females) indicate affected subjects, open symbols indicate unaffected subjects, and gray symbols indicate unknown disease status. Diamonds indicate not-relevant subjects and the numbers within them are the number of subjects. Diagonal lines indicate dead subjects. Arrows identify the analyzed subjects. WT indicates homozygotic carriers of rs58238559 major allele while M indicates the heterozygotic subjects for rs58238559 variant. Ages are given beneath the individual’s ID number.