Skip to main content

Table 8 Most significant interactions detected through exhaustive search after main effect SNPs removal

From: Filter-free exhaustive odds ratio-based genome-wide interaction approach pinpoints evidence for interaction in the HLA region in psoriasis

rs number Chromosome Position Marginal effect p-value a I OR R 2b
p-value
SNP1 SNP2 SNP1 SNP2 SNP1 SNP2 SNP1 SNP2
rs2254556 rs9267532 6 6 31,374,854 31,672,202 0.008 0.076 1.22E-22 5.23 0.002
rs9267532 rs2523518 6 6 31,672,202 31,373,351 0.076 0.006 3.15E-22 5.15 0.002
rs2596437 rs9267532 6 6 31,371,309 31,672,202 0.006 0.076 7.56E-22 5.1 0.002
  1. aBold data are genome-wide significant interactions. bR2 were calculated using controls only.