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Table 5 Results from conditional search, restricted to pairs of previously implicated SNPs

From: Filter-free exhaustive odds ratio-based genome-wide interaction approach pinpoints evidence for interaction in the HLA region in psoriasis

First GWAS SNP Second GWAS SNP FORCE PLINK FastEpistasis
rs number Chromosomal location rs number Chromosomal location I OR Empirical p-value p-value
rs10484554 6p21.33 rs27524 5q15 6.846 0.008882 0.003095
rs10484554 6p21.33 rs3134792 6p21.33 1.068 0.3014 0.007746
rs2201841 1p31.3 rs3213094 5q33.3 4.737 0.02952 0.012373
rs3134792 6p21.33 rs4795067 17q11 3.188 0.07419 0.012783
rs20541 5q31 rs17716942 2q24 6.987 0.008212 0.013389
rs702873 2p16 rs4795067 17q11 3.414 0.06466 0.014129
rs10484554 6p21.33 rs4795067 17q11 2.597 0.1071 0.018096
rs610604 6q23 rs17716942 2q24 6.591 0.01025 0.023261
rs3213094 5q33.3 rs12580100 12q13.2 5.132 0.02349 0.028993
rs4649203 1p36 rs240993 6q21 2.270 0.1319 0.037791
rs4649203 1p36 rs702873 2p16 1.237 0.266 0.041136
rs3134792 6p21.33 rs27524 5q15 11.840 0.000581 0.041483
rs702873 2p16 rs2546890 5q33.3 0.804 0.37 0.041729
rs27524 5q15 rs17716942 2q24 5.280 0.02158 0.045812
rs610604 6q23 rs6701216 1q21 4.289 0.03837 0.057701
rs2201841 1p31.3 rs2546890 5q33.3 2.587 0.1077 0.059206
rs27524 5q15 rs7993214 13q14.11 3.596 0.05793 0.059609
rs3134792 6p21.33 rs3213094 5q33.3 2.610 0.1062 0.072999
rs702873 2p16 rs2201841 1p31.3 1.669 0.1964 0.083717
rs10484554 6p21.33 rs12580100 12q13.2 2.535 0.1113 0.086631
rs4649203 1p36 rs6701216 1q21 3.518 0.06072 0.086671
rs2201841 1p31.3 rs27524 5q15 1.666 0.1968 0.088785
rs4112788 1q21.3 rs7993214 13q14.11 1.546 0.2137 0.090419
rs240993 6q21 rs7993214 13q14.11 1.896 0.1685 0.096038
rs6701216 1q21 rs8016947 14q13 1.087 0.2971 0.100508